NIR chemical imaging can be used to determine pharmaceutical blend homogeneity and tablet uniformity
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Chemical Imaging Applications

ISys - Data Analysis for Chemical Imaging

Chemical Imaging can be used in many industries to solve a variety of problems in the laboratory, quality control, quality assurance or process environments. The applications of NIR Chemical Imaging include the following:

  • Non-destructive determination of pharmaceutical tablet component distribution and concentrations
  • Assessment of pharmaceutical blend homogeneity
  • Determining domain and particle size and distribution of chemical components in heterogeneous mixtures
  • Root cause analysis and out-of-spec determinations
  • Identification and discrimination of polymorphic forms


 


Applications:

 
Chemical Imaging applications - Identifying Counterfeits
 
Identifying Counterfeits
NIR chemical imaging is a powerful analytical technique that is being used increasingly in the fight against counterfeit drugs. Capable of simultaneously analyzing a number of tablets or capsules, NIR imaging can be automated to provide rapid "genuine/ fake" detection.
Chemical Imaging applications - Identifying Counterfeits
 
Chemical Imaging applications - tablet analysis
 
Non-destructive tablet analysis
Non-destructive NIR chemical imaging provides a fingerprint of the tablet’s production properties, and ultimately, its performance.
Chemical Imaging applications - tablet analysis
 
Chemical Imaging application - blend uniformity
 
Blend uniformity
NIR Chemical Images can be analyzed statistically to measure blend homogeneity within individual tablets or between multiple tablets.
Chemical Imaging application - blend uniformity
 
Chemical Imaging applications - Domain statistics calculation
 
Domain statistics calculation
NIR Chemical Imaging can be used to determine domain statistics and the distribution of chemical components in heterogeneous mixtures
 
Chemical Imaging applications - Domain statistics calculation
 
Chemical Imaging applications - Impurity identification
 
Contaminant and impurity identification
NIR Chemical Imaging supplies complete spectral information at each pixel and can detect even minute quantities of impurities or contaminants.
 
Chemical imaging applications - Contaminant and impurity identification
 
Tablet Uniformity
 
Tablet Uniformity
NIR Chemical Imaging can provide both intra- and inter-tablet uniformity data during routine manufacturing applications
 
Tablet Uniformity
 
Chemical Imaging applications in thepharmaceutical industry
 
Pharmaceutical applications
NIR Chemical Imaging can be used in the pharmaceutical industry to determine hydration, locate contaminants, and measure coating and layer thickness
 
Chemical Imaging applications in thepharmaceutical industry

 

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This product and/or its use may be covered by US patent numbers 6483112 and 6,690,464. Other patents pending.