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Product Group
Zetasizer range
Further information:
Zetasizer Nano Series - Specification
Customer stories
Although we’ve had the Zetasizer Nano only since November last year, it is clearly proving to be the easiest to use and most reliable of all the light scattering systems we’ve had in the lab. Whether sample concentration is low or high, it is never a problem, and is all taken care of with a single button, fully automated measurement. Data are clean and easy to interpret. Whereas light scattering systems we’ve used previously have proved too sensitive to contaminating particles, this is overcome with the Zetasizer Nano.read more
- Fred Hutchinson Cancer Research Center (SIC)
| Zetasizer News - changes in specification |  |
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Size measurement |
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| Maximum particle size range (diameter): | 0.3nm - 10µm** |  |
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| 0.3nm - 5µm†† | |
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| Minimum sample volume: | 12µL | |
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| 20µL | |
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| Minimum sample concentration: | 0.1mg/mL Lysozyme 0.1ppm polystyrene latex (60nm) |
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| Maximum sample concentration: | 40%w/v* |
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| Size measurement in continuous flow for use as SEC chromatography detector : | Flow rate maximum 1mL/min |
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Zeta potential measurement |
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| Particle size range (diameter): | 3.8nm - 100µm† | |
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| Zeta potential range: | No practical limits exist |
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| Electrophoretic mobility range: | Minimum Zero No practical upper limit exists |
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| Conductivity range: | 0 to 200mS/cm | |
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| Sample concentration range: | Up to 40%w/v† | |
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| Minimum sample volume: | 750µL (Folded capillary cell) 750µL (Dip cell) 150µL (High concentration cell) |
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Molecular weight measurement |
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| Absolute molecular weight range using Debye plot: | 980Da - 2x107 Da† | |
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| 9,800Da - 2x107 Da† | |
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| Molecular weight range estimated from Hydrodynamic diameter: | 342Da - 2x107 Da† | |
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| Minimum sample volume: | 12µL | |
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| 20µL | |
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| Minimum volume for automated measurement: | 4mL | |
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Trend measurement |
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| Standard: | Size Vs Time or Temperature | |
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| Zeta potential Vs Time or Temperature | |
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| Using optional MPT-2 autotitrator: | Size as a function of pH, conductivity or additive concentration | |
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| Size as a function of pH, or additive concentration | |
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| Zeta potential as a function of pH, conductivity or additive concentration | |
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General specifications |
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| Temperature range: | 0ºC to 90ºC* | |
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| Condensation control: | Purge facility using dry air. | |
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| Patents granted: | NIBS
DE 19725211 US 6,016,195 JP 2,911,877 EP 0 884 580 designated GB, FR, AU, SW, BE |
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M3 "High & Low Frequency Electrophoresis"
GB 2,361,772 EP 1 154 266 designated DE, FR US 09/843339 JP 2001-134510 |
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| Laser: | 4mW He-Ne, 633nm | |
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| Laser attenuator : | Automatic, transmission 100% to 0.0003% | |
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| Detector : | Avalanche photodiode,Q.E > 50% at 633nm |
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| Product laser class: | Class 1 compliant, EN 60825-1:2001 and CDRH | |
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| Size : | 320mm, 600mm, 260mm (W,D,H) | |
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| Weight : | 21kg | |
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| Recommended computer specification: | Pentium PC 2GHz, 128MByte RAM, 80MByte free hard disk space, 1024 x 768 screen resolution, CD-ROM drive, Windows XP Pro (Service pack 2 or higher) or VISTA Business or Ultimate. One free USB port. Note. A laptop computer with a USB port can be used with all Zetasizer Nano systems and MPT-2 autotitrator. |
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Options |
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| 50mW 532nm laser as replacement for standard He-Ne Laser: | For the measurement of samples not compatible with the standard 633nm He-Ne laser | |
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| Narrow band filter: | To improve signal quality for fluorescent samples | |
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| Advanced data processing software: | Advanced system utilities and additional analysis algorithms | |
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| Regulatory compliance: | 21 CFR part 11 operating mode software. | |
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| Extended temperature: | Increase of temperature range to 0°C - 120°C | |
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Site requirements |
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| Power requirements: | AC 100-240V, 50-60Hz, 100W | |
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| Ambient operating Temperature: | 10ºC - 35ºC. | |
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| Humidity : | 10 – 90% non-condensing. | |
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| Location: | Normal laboratory conditions, out of direct sunlight. |
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| Dry air for operation at temperatures below the dew point : | DIN8573-1, oil class 1, water class 3, pressure 200+/-20kPag. Fitting M5 female thread to BS3643. | |
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Note:
* Temperature accuracy, 0.1°C at 25°C, 0.2°C at 0°C and 0.5°C at 90°C, 1°C at 120°C
** Peak mode range (diameter), 0.6nm - 8.9 microns, sample dependent
† Sample dependent
†† Peak mode range (diameter), 0.6nm - 3 microns, sample dependent
