Spray Drying Process Control Using Malvern Particle Size Analyzers

Automatic process control and on-line QC place high demands on the uptime performance of a particle size analyzer, and all Malvern systems are designed from the outset for process use. Key to their success is the ability to be installed almost anywhere, thanks to strong interfacing capabilities, both to the process and to the control system.

• Highly robust high speed instruments
• Hygienic fittings to ensure ease of cleaning between production batches of entire sample path
• Range of options for use in a diverse range of industries from metal powders to pharmaceutical / GAMP4 environments

The particle size and dust loading analyzers are used to both optimize and continually monitor the production of solid and liquid particulates produced by a range of spray drying and atomizer processes. Malvern works with a range of partners who supply plant equipment and recommend the use of Malvern analyzers in their processes.

Below is a table outlining the different analysis solutions available:

Environment		Analyzer		Accessories		Process Interface		Useful for:
Dry powders		0.1-1000µm, Static integrated analyzer: Non-IS: Insitec T IS: Insitec X		Various automated options Pharmaceutical kit option		Dilute streams: In-line dry flow cells		Atomizer/spray drier exit for nozzle speed/feed pressure control
						Medium-high concentration: Jet-stream eductor Auger		Classifier (final grade) exit, final grade QC
						At-line: manual sampling accessory		General near-process QC
		50-2500µm, Static integrated analyzer Non-IS: Parsum IPP70S IS: Parsum IPP70SE		Analogue 4-20mA outputs		In-line probe with variety of custom measurement zones		Spray drying in detergent manufacture
Particles in liquid medium		0.1-1000µm analyzer: Insitec S		Various automated options		Continuous streams: In-line flow cell 4Hz measurement		Separator optimization
		0.1-1000µm analyzer: Insitec S		Various automated options		Various optical bridges		Nozzle optimization
Process trouble shooting		0.1-1000µm, Mobile analyzer: Insitec Voyager		"plus" pack, (automation option) Non-IS: Insitec T IS: Insitec X Pharmaceutical kit option		On-line: Jet-stream eductor At-line: manual sampling accessory		Atomizer setup on multiple process lines General plant optimization