Skip to left navigation

Skip to page content

Find us on...
Nanoparticles

The small size of nanoparticles is of utmost importance in order for them to maintain their unique optical, electronic, thermal and chemical properties. Measuring their size is therefore critical to understanding these nano-scale materials.

Zeta potential is another important parameter that is related to nanoparticle stability or aggregation in a dispersion, and can have significant implications on product performance.

Light scattering, especially dynamic light scattering, and electrophoretic light scattering are now the standard techniques for measuring the size and zeta potential of dispersed nanoparticles. Two new techniques, Nanoparticle Tracking Analysis (NTA), and also Resonant Mass Measurement (RMM) can also be used for sizing nanoparticles as well as counting the number of particles present in a sample, and both are especially suited to polydisperse samples. Nanoparticle Tracking Analysis (NTA) is provided via the Malvern NanoSight range of instruments, and RMM is available via Archimedes.

Malvern offers a range of fast, reliable and simple to use systems that incorporate light scattering technology, resonant mass measurement or nanoparticle tracking analysis (NTA), which are used to:

  • Determine nanoparticle size.
  • Detect the formation of aggregates in a sample containing nanoparticles.
  • Measure zeta potential for an indication of nanoparticle stability.
  • Count the number of nanoparticles present in a sample.
 
 

Resource center search

Free access to exclusive content including webinars, presentations, application notes, technical notes, whitepapers and more. Enter your search term in the box and use the drop down boxes to filter the results.

Reset filters
Items shown: 5, 10, 20, ALL
Sort by: Date or Alphabetical
Previous page Showing results 1 - 5 of 70 Next page
NanoSight NTA Concentration Measurement Upgrade Technical Note (English)

NanoSight instruments with upgraded concentration measurement have increased concentration measurement accuracy and repeatability. This provides improved measurement robustness and removes the influence of user settings. Data is shown here that illus...


Keywords: Nanoparticles English Technical Note Particle concentration Particle size NanoSight range Nanoparticle Tracking Analysis 

Nanoparticle Tracking Analysis (NTA) for time-resolved, reproducible nanoparticle characterization under environmentally relevant conditions Poster (English)

With ever-increasing amounts of nanomaterials being commercially produced and utilized, there exists a need to determine the lifecycle and fate of these materials, with an understandable focus on potentially toxic effects. This poster describes ...


Keywords: Nanoparticles English Poster Particle concentration Particle size NanoSight range Ecotoxicology Nanotoxicology Nanoparticle Tracking Analysis Fluorescence detection 


Nanoparticle Tracking Analysis (NTA) characterization of polymer colloids Poster (English)

NTA was successfully used to characterize a broad range of polymer particles and polymer suspensions for various applications including thermo responsive polymers, mix size polymer microspheres as well as drug delivery vesicles.


Keywords: Nanoparticles English Poster Particle concentration Particle size Colloids Biological drug characterization and development NanoSight LM10 Nanoparticle Tracking Analysis Fluorescence detection 

Determining fluorescence Limit of Detection with Nanoparticle Tracking Analysis (NTA) Application Note (English)

NanoSight instruments can also operate in fluorescence mode where only fluorescently labeled particles are detected and measured. Here, we describe an experiment to determine the fluorescence limit of detection for a given fluorophore.Insert abstract...


Keywords: Nanoparticles English Application Note Particle concentration Particle size Biological drug characterization and development Bioformulation development Biopharmaceutical manufacturing Antibodies and derivatives NanoSight LM10 Nanotoxicology Exosomes and microvesicles Nanoparticle Tracking Analysis Fluorescence detection 
Previous page Showing results 1 - 5 of 70 Next page

Glossary

Contact sales Register now

Upcoming webinar

Fluorescence Masterclass - The basics
(June 16 2015)

More information

Instruments featured in this page

 

NTA is a relatively new addition to the lab but is already bringing value to several areas of research. For example, the ability to visualize particles over time is allowing one research group developing self-assembling proteins to trace the changes in size of their molecules over time to better understand the dynamics of aggregation.


Dr Krystelle Mafina, Queen Mary University, United Kingdom

Read full details