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Nanoparticles

The small size of nanoparticles is of utmost importance in order for them to maintain their unique optical, electronic, thermal and chemical properties. Measuring their size is therefore critical to understanding these nano-scale materials.

Zeta potential is another important parameter that is related to nanoparticle stability or aggregation in a dispersion, and can have significant implications on product performance.

Light scattering, especially dynamic light scattering, and electrophoretic light scattering are now the standard techniques for measuring the size and zeta potential of dispersed nanoparticles. Two new techniques, Nanoparticle Tracking Analysis (NTA), and also Resonant Mass Measurement (RMM) can also be used for sizing nanoparticles as well as counting the number of particles present in a sample, and both are especially suited to polydisperse samples. Nanoparticle Tracking Analysis (NTA) is provided via the Malvern NanoSight range of instruments, and RMM is available via Archimedes.

Malvern offers a range of fast, reliable and simple to use systems that incorporate light scattering technology, resonant mass measurement or nanoparticle tracking analysis (NTA), which are used to:

  • Determine nanoparticle size.
  • Detect the formation of aggregates in a sample containing nanoparticles.
  • Measure zeta potential for an indication of nanoparticle stability.
  • Count the number of nanoparticles present in a sample.
 
 

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Measuring small volumes of nanoparticles using the Mastersizer 3000 and Hydro SV Application Note (English)

Nanoparticles can be difficult to produce, and are often synthesized in small quantities and dispersed in expensive solvents. The Hydro SV is allows us to measure the particle size distribution samples dispersed in 6-7ml of dispersant, and is therefo...


Keywords: Development Nanoparticles Suspensions, slurries and pastes English Application Note Mastersizer 3000 Particle size Laser diffraction Paints, inks and coatings 

Design and formulation of nanomedicines including liposomes Whitepaper (English)

In this white paper the specific mechanisms by which nanoparticles are designed and formulated for therapeutic purposes and in which NTA has had a significant part to play is discussed.


Keywords: Nanoparticles English Whitepaper Particle concentration Particle size Liposomes and micelles Biological drug characterization and development NanoSight range Nanoparticle Tracking Analysis 

Studying nanoparticle-based drug delivery and targeting with Nanoparticle Tracking Analysis Whitepaper (English)

This white paper addresses some of the latest work reported in the literature in which Nanoparticle Tracking Analysis (NTA) has been proposed, used and assessed in the study of nanoparticle-based drug delivery and targeting


Keywords: Nanoparticles English Whitepaper Particle concentration Particle size Biological drug characterization and development NanoSight range Nanoparticle Tracking Analysis 

Assessing Nanoparticle Toxicity in Waste Water using Nanoparticle Tracking Analysis Whitepaper (English)

Nanoparticle Tracking Analysis (NTA) has found use in a variety of investigations researching the toxicity and environmental impact of nanoparticles. Here we discuss various publications in which NTA has been used to measure particle size and concent...


Keywords: Nanoparticles English Whitepaper Particle concentration Particle size NanoSight range Nanotoxicology Nanoparticle Tracking Analysis 

Measuring environmental impact of nanomaterial wastes and contaminants using Nanoparticle Tracking Analysis Whitepaper (English)

The increasing number of nanomaterial based consumer products raises concerns about their possible impact on the environment. Suitable methods for their analysis are a particular problem in this regard. This white paper reviews the use of Nanoparticl...


Keywords: Nanoparticles English Whitepaper Particle concentration Particle size NanoSight range Nano regulations Nanoparticle Tracking Analysis 
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