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Microrheology involves tracking the motion of dispersed tracer particles of known size by Dynamic Light Scattering (DLS) and determining the rheological properties of the sample using the Generalized Stokes-Einstein Relation. DLS Microrheology is a passive microrheology technique, whereby the colloidal probe particles only undergo thermal fluctuations in a system at thermodynamic equilibrium.
DLS Microrheology is applicable for the rheological characterization of low viscosity and weakly-structured complex fluids, such as dilute solutions of polymers and surfactants through to concentrated protein formulations. For these types of materials, Microrheology offers significant advantages:
Applications of DLS Microrheology include:
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The whitepaper discusses some basic principles of polymer solution rheology and how it can be measured and manipulated to optimize rheological behaviour
This poster presents an optimized methodology for making microrheology measurements on a Zetasizer Nano ZS/ZSP
This poster discusses ways to extend the shear rate and frequency range beyond traditional limits of a rotational rheometer range using creep testing, microrheology and microfluidics
This poster shows why rotational rheometry and microrheology are complementary tools for characterizing the viscoelastic properties of macromolecules in solutions
Measurement and characterization of binding interactions between proteins and low-molecular weight (LMW) ligands are a focus of academic research and drug discovery. Isothermal titration calorimetry (ITC) directly measures heat released or absorbed i...
(Webinar - Recorded)
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