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The molecular weight of proteins, synthetic and natural polymers is a direct indicator of product performance and activity.
Understanding this and other molecular parameters is key to controlling product performance in a wide variety of applications areas including:
Malvern’s advanced GPC/SEC detectors, which include low angle and right angle light scattering (LALS and RALS) and multi-angle light scattering (SEC-MALS), are designed to measure absolute molecular weight with unparalleled accuracy. Complete systems such as the TDAmax form and out-of the-box solution, while add-on detectors such as the SEC-MALS 20 and the Zetasizer µV allow you to upgrade an existing GPC/SEC system to measure absolute molecular weight.
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Different samples of commercially available PLGA were analyzed to compare their absolute molecular weight from light scattering to those quoted with the product. Additionally, the Mark-Houwink plots of different examples containing different ratios o...
A review of the methods available for measuring the key characteristics of polymers focusing on the benefits and value of gel permeation/size exclusion chromatography (GPC/SEC). Much of the paper talks exclusively about polymers, however many of the ...
In this application note, we describe the analysis of a semi-purified protein mixture containing β-amylase. Step-by-step, we show how different properties of the proteins elicit a specific response in each detector and how the coupling this data can...
During this webinar, we introduces the latest innovations in SEC technology, and discuss how the new OMNISEC system will assist your protein characterization challenges. Focusing on applications, the webinar compares the capabilities of the system wi...
A series of dextran samples ranging in molecular weight from about 1– 650 kDa are characterized using OMNISEC. Structural comparisons to other polysaccharides, gum arabic and pectin are presented
(Webinar - Recorded)
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