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The molecular weight of proteins, synthetic and natural polymers is a direct indicator of product performance and activity.
Understanding this and other molecular parameters is key to controlling product performance in a wide variety of applications areas including:
Malvern’s advanced GPC/SEC detectors, which include low angle and right angle light scattering (LALS and RALS) and multi-angle light scattering (SEC-MALS), are designed to measure absolute molecular weight with unparalleled accuracy. Complete systems such as the TDAmax form and out-of the-box solution, while add-on detectors such as the SEC-MALS 20 and the Zetasizer µV allow you to upgrade an existing GPC/SEC system to measure absolute molecular weight.
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Investing in a new GPC/SEC system is a big decision with many factors to consider. This white paper lists the key items that you should think about when buying a new system and discusses the reasons for their importance. Finally, it discusses what M...
Correctly targeting a drug product’s delivery location and defining its release profile are critical challenges and the subject of a great deal of research. The role of polymers in drug delivery applications is growing, with particular emphasis on ta...
Gel Permeation Chromatography (GPC), also known as Size Exclusion Chromatography (SEC), is a very popular analytical technique for characterizing natural and synthetic polymers. Malvern offers a range of multi-detector GPC systems for the advanced ch...
The derived count rate is the normalized count rate taking into account the attenuation factor used
The drug delivery polymer polyglutamic acid was conjugated with different amounts of Doxorubicin and characterized using advanced multi-detector GPC to measure drug content, molecular weight and structure
(Webinar - Recorded)
OMNISEC: Demo at your desk
(September 29 2016)
The technical support that we’ve received has been a deciding factor in our decision to continue to work with Malvern. Malvern systems also provide the cutting-edge performance and reliability that we need.
Domino Printing Sciences plc
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