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By far the most important physical property of particulate samples is particle size. Measurement of particle size distributions is routinely carried out across a wide range of industries and is often a critical parameter in the manufacture of many products. The particle size distribution has a direct influence on material properties such as:

  • Reactivity or dissolution rate - e.g. catalysts, tablets.
  • Stability in suspension – e.g. sediments, paints.
  • Efficacy of delivery – e.g. asthma inhalers.
  • Texture and feel – e.g. food ingredients.
  • Appearance – e.g. powder coatings and inks.
  • Flowability and handling – e.g. granules.
  • Viscosity – e.g. nasal sprays.
  • Packing density and porosity – e.g. ceramics.

Measuring particle size distributions and understanding how they affect your products and processes can be critical to the success of many manufacturing businesses. Malvern Instruments offers leading instrumentation for all types of particle size analysis and characterization from sub-nanometer to millimeters in particle size.

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Novel analytical technologies for product deformulation - Part 1 Webinar - Live (English)

Successful development of generic nasal drug products requires sponsors to understand how the dose is atomized by the chosen pump device in order to achieve bioequivalence. In addition, the impact of atomization of the particle size of the dr...

Date:
August 5 2014
Language:
English

Keywords: English Particle size Raman spectroscopy Webinar - Live Eastern Time Pharmaceutical development Drug discovery Pharmaceutical formulation and development 


Scoping the Design Space for Generic Nasal Sprays Article (English)

In this article, Deborah Huck-Jones, PhD, Product Manager, Analytical Imaging; and Paul Kippax, PhD, Micrometrics Product Group Manager & Pharmaceutical Portfolio Manager, both of Malvern Instruments, discuss analytical methods that can b...

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Keywords: English Article Spraytec Particle shape Particle size Pharmaceutical formulation and development Orally inhaled and nasal drug products Morphologi range 

Differentiation and characterization of subvisible particulates in therapeutic protein products Application Note (English)

This application note provides an example of how Archimedes can be used to detect and quantify the formation of protein sub-visible particles and the introduction of silicone oil droplets, in response to shear stress.


Keywords: Contaminants and foreign particles English Application Note Particle concentration Particle size Viruses and vaccines Resonant mass measurement Protein aggregation Proteins Biopharmaceutical development Archimedes 

Characterization of Single Wall Carbon Nanotubes (SWNTs) by combining Dynamic Light Scattering and Raman Spectroscopy Whitepaper (English)

The combination of DLS and Raman spectroscopy offers the ability to measure the length, diameter, and chirality of carbon nanotubes in a single experiment. These parameters can be used with existing empirical knowledge of nanotubes to pre...


Keywords: English Whitepaper Molecular structure Particle size Dynamic Light Scattering Raman spectroscopy Electronic displays Batteries Fuel cells Solar cells Carbon nanotubes Zetasizer Helix 
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Novel analytical technologies for product deformulation - Part 1
(August 5 2014)

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