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By far the most important physical property of particulate samples is particle size. Measurement of particle size distributions is routinely carried out across a wide range of industries and is often a critical parameter in the manufacture of many products.

Measuring particle size distributions and understanding how they affect your products and processes can be critical to the success of many manufacturing businesses. Malvern Instruments offers leading instrumentation for all types of particle size analysis and characterization from sub-nanometer to millimeters in particle size.

Use the table below to help choose the right technology and particle size instrument for your needs:


Particle
size range*

0.1nm

1nm

10nm

100nm

1µm

10µm

100µm

1mm

10mm

 
 
 
 
 
 
 
 
 
 
 

Dynamic Light Scattering
<1nm to >1µm

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 

Resonant Mass Measurement**
50nm to 5µm

 
 
 
 
 
 
 
 
 
 

Laser
Diffraction

<100nm to >2mm

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 

Automated
Imaging

<1µm to >3mm

 
 
 
 
 
 
 
 
 
 

*all particle size ranges are sample dependent
**particle size ranges are sample and sensor dependent.

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Applying complementary particle techniques for assessing comparability and biosimilarity of therapeutic products Webinar - Live (English)

Significant advances have been made in analytical technology for the characterization and identification of particles present in pharmaceutical products. With these advances comes a tremendous amount of new data with which to characterize biologics, ...

Product:
Archimedes,Zetasizer range,Viscotek SEC-MALS,Morphologi G3-ID,NanoSight range
Date:
September 20 2016
Language:
English


What is Multiple Scattering? FAQ

Multiple scattering refers to the phenomenon where photons scattered from the sample are re-scattered from neighboring particles prior to reaching the instrument detector.



Number Fluctuations: What Are They and How Are They Recognised? FAQ

Number fluctuations are defined as variations in the number of particles within the scattering volume during the course of a dynamic light scattering (DLS) measurement.



Manufacturing and characterizing spray dried products: Part 2 – Measuring powder characteristics Webinar - Recorded (English)

Spray drying, which produces a dry powder from a liquid or slurry, is one of the most popularly-used continuous drying processes in which a liquid in the form of an emulsion, wet slurry or suspension is sprayed via a spray nozzle or a rotary atomizer...

Product:
Mastersizer range
Date recorded:
July 14 2016
Language:
English


Rapid Generic Pharmaceutical Product Development Webinar - Recorded (English)

In a recent newsletter, the US FDA highlighted the important role Morphologically-Directed Raman Spectroscopy (MRDS) can play in supporting the development of generic drug products. The component-specific particle size and shape distribution data gen...

Product:
Morphologi G3-ID
Date recorded:
July 12 2016
Language:
English

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Applying complementary particle techniques for assessing comparability and biosimilarity of therapeutic products
(September 20 2016)

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