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Zeta potential is a measure of the magnitude of the electrostatic or charge repulsion/attraction between particles, and is one of the fundamental parameters known to affect stability. Its measurement brings detailed insight into the causes of dispersion, aggregation or flocculation, and can be applied to improve the formulation of dispersions, emulsions and suspensions.

Speed of introduction of new formulations is the key to product success. Measurement of zeta potential is one of the ways to shorten stability testing by reducing the number of candidate formulations, hence reducing the time and cost of testing as well as improving shelf life.

In water treatment, monitoring dosage using zeta potential measurements can reduce the cost of chemical additives by optimizing the dosage control.

The measurement of zeta potential has important applications in a wide range of industries including; ceramics, pharmaceuticals, medicine, mineral processing, electronics and water treatment.

Malvern Instruments offer leading instrumentation for the measuring of zeta potential, or electrophoretic mobility. The Zetasizer Nano provides a simple, fast and accurate way to measure zeta potential, and uses a unique disposable capillary cell to ensure that there is no cross contamination between samples. The NanoSight NS500 measures single particle zeta potential distributions which can be measured simultaneously with particle size, concentration and when operating in fluorescence mode.

Related products

Zetasizer range The worlds most widely used system for nanoparticle, colloid and protein size, zeta potential and molecular weight measurements. Image
Molecular size, Particle size, Molecular weight, Zeta potential
Temperature range
Particle size range
0.3nm to 10µm
Dispersion type
Dynamic Light Scattering, Static Light Scattering, Size Exclusion Chromatography, Electrophoretic Light Scattering
More information
NanoSight NS500 Single particle zeta potential platform with integrated fluidics for automation. Image
Particle size, Particle concentration, Protein aggregation, Zeta potential
Particle size range
10nm to 2000nm
Nanoparticle Tracking Analysis, Electrophoretic Light Scattering
More information

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Suspension Stability: Why particle size, zeta potential and rheology are important Poster (English)

Why particle size, zeta potential and rheology are important. This poster discusses the importance of particle size, zeta potential and rheology for dispersion stability and how they can be manipulated to enhance stability

Keywords: Suspensions, slurries and pastes English Poster Particle size Rheology and viscosity Zeta potential Electrophoretic Light Scattering Laser diffraction Rheometry - rotational 

Using Automated Light Scattering Measurements to Support Predictive Protein Formulation Screening Article (English)

High concentration, low-viscosity, stable therapeutic protein formulations are needed to enable low-volume parental administration. This article explores how a fully automated light scattering system supports the rapid screening of small volume sampl...

Keywords: Emulsions and creams English Article Bohlin Gemini 2 Kinexus pro+ Particle size Rheology and viscosity Zeta potential Dynamic Light Scattering Electrophoretic Light Scattering Rheometry - rotational Personal care Zetasizer Nano S Zetasizer Nano ZS Zetasizer Nano ZSP 

How to characterize and optimize inkjet inks Part 2 Webinar - Recorded (English)

Achieving product stability is a critical aspect of ink formulation. Modern inks are typically colloidal suspensions of multiple components in an organic or aqueous continuous phase. The functionality of the finished product relies on maintaining sus...

Zetasizer Nano range,Mastersizer range
Date recorded:
October 21 2014

Keywords: Suspensions, slurries and pastes English Mastersizer range Particle size Rheology and viscosity Zeta potential Laser diffraction Pigments and toners Paints, inks and coatings Webinar - Recorded Eastern Time Zetasizer Nano range 

Zeta potential measurements of high conductivity colloidal samples Application Note (English)

The diffusion barrier technique can be used for any colloidal sample with high conductivity. This application note discusses the application of the diffusion barrier technique to high conductivity samples through the measurement of various liposome s...

Keywords: Nanoparticles English Application Note Zeta potential Colloids Liposomes and micelles Zetasizer Nano range 

How good is on-line zeta-potential measurement in water treatment? Article (English)

In this article we look at what zeta potential is and the potential role that on-line zeta potential monitoring can play in optimizing the water treatment process, specifically flocculation control. The applicability of zeta potential is illustrated ...

Keywords: English Article Zeta potential Electrophoretic Light Scattering Water treatment Zetasizer Nano range 
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