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MicroCal instruments are powerful, analytical tools used to study biological systems. These include interactions between molecules as well as changes in conformation such as protein unfolding. The technique is very convenient requiring only minimal assay development and NO labelling. The range includes both Differential Scanning and Isothermal Titration calorimetry.

MicroCal systems are used in a wide range of applications from basic research to the discovery and development of small molecule drugs, biotherapeutics and vaccines. Our customers include pharmaceutical, biotech, academic and governmental research institutions worldwide.

MicroCal DSC range Powerful analytical tools for characterizing the stability of proteins and other biomolecules DSC_set
Measurement
Microcalorimetry, Label-free analysis
Temperature range
-10°C to 130°C
Sample throughput
2per 24h day to 50per 24h day
Technology
Differential Scanning Calorimetry
More information
MicroCal ITC range Determine the binding parameters of biomolecules in a single analysis ITC_set
Measurement
Microcalorimetry, Label-free analysis
Temperature range
2°C to 80°C
Sample throughput
4per 24h day to 42per 24h day
Technology
Isothermal Titration Calorimetry
More information
 
 

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Microcalorimetry as a tool for structural biology Webinar - Live (English)

The success rate for protein- or RNA/DNA-ligand co-crystallization can be significantly improved by performing preliminary biophysical analyses. Among suitable biophysical approaches, isothermal titration calorimetry (ITC) is certainly a method of ch...

Product:
MicroCal Auto-iTC200,MicroCal iTC200,MicroCal VP-ITC
Date:
March 24 2015
Language:
English

Keywords: English Webinar - Live Eastern Time Proteins MicroCal Auto-iTC200 MicroCal iTC200 MicroCal VP-ITC Isothermal Titration Calorimetry Label-free analysis 

MicroCal PEAQ-ITC live launch Webinar - Recorded (English)

Find out how the new MicroCal PEAQ-ITC will help you... Biochemistry & molecular recognition Investigate signaling pathways Gain new insights into the structure/function relationships of important biomolecular interactions Perform binding stu...

Product:
MicroCal range,MicroCal PEAQ-ITC Automated,MicroCal PEAQ-ITC,MicroCal PEAQ-ITC range,MicroCal ITC range
Date recorded:
March 3 2015
Language:
English

Keywords: English Webinar - Recorded Greenwich Time Biopharmaceutical development MicroCal range MicroCal ITC range Isothermal Titration Calorimetry Microcalorimetry Label-free analysis MicroCal PEAQ-ITC range MicroCal PEAQ-ITC MicroCal PEAQ-ITC Automated 

Use of the new MicroCal PEAQ-ITC system for measurement and characterization of a broad range of protein-LMW compound interactions Whitepaper (English)

Measurement and characterization of binding interactions between proteins and low-molecular weight (LMW) ligands are a focus of academic research and drug discovery. Isothermal titration calorimetry (ITC) directly measures heat released or absorbed i...


Keywords: English Whitepaper Microrheology Isothermal Titration Calorimetry Label-free analysis MicroCal PEAQ-ITC range 

Addressing the needs of drug discovery with the MicroCal PEAQ-ITC instruments Whitepaper (English)

Measurements and characterization of binding interactions between proteins and low-molecular weight ligands are fundamental for drug discovery. Among the most recognized challenges in characterizing binding interactions are (1) the need to accurately...


Keywords: English Whitepaper Isothermal Titration Calorimetry Microcalorimetry Label-free analysis MicroCal PEAQ-ITC range 

MicroCal Auto-ITC200 user manual (English) User Manual (English)

User manual for the MicroCal Auto-ITC200 instrument


Keywords: English User Manual MicroCal Auto-iTC200 
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