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The Morphologi G3-ID provides a unique capability, combining automated static imaging features of the Morphologi G3 with chemical identification of individual particles using Raman spectroscopy to enable the measurement of component specific particle size and particle shape distributions.


This fully automated instrument is designed to allow both particle characterization scientists with limited spectroscopy experience and more experienced spectroscopists to get an in-depth understanding of their particulate samples. Key features:

  • Measures particle size, shape and chemical identity in one platform.
  • Automates Morphologi G3 with Kaiser Optical Systems RamanRxn1 spectrometer.
  • Integrated dry powder dispersion with accurate dispersion energy control automates sample preparation for consistent measurements of both fragile and robust materials.
  • Simple SOP operation from sample dispersion through to size, shape and chemical analysis.
  • Automatic selection, targeting and chemical classification of 1000’s of individual particles.
  • Export function for third party forensic library investigations.
  • Single point manual targeting mode for manual selection of particles for chemical analysis.
  • Powerful and intuitive software interface making both visual and statistical interpretation of your data easier than ever.

How it works

The Morphologi G3-ID is ideally suited to solving complex particle characterization problems where component-specific particle size and shape distributions are required. This includes measurement of components within powder blends and suspensions, along with the identification of contaminant or suspicious particles within product formulations.

The measurement workflow can be divided into three distinct steps, each of which can be automated:

  • Sample preparation
    This step is critical to getting good results; spatial separation of individual particles and agglomerates is the goal. The Morphologi G3SE has an integrated dry powder disperser which makes preparing dry powder samples easy and reproducible. The applied dispersion energy can be precisely controlled, enabling the measurement process to be optimised for a range of material types. Dispersion is achieved without explosively shocking the particles, avoiding the damage of fragile particles while ensuring strongly agglomerated materials are dispersed. Effective dispersion of fibres can also be achieved.
  • Particle size and shape measurement
    The instrument automatically measures the size and shape of particles in a dispersed sample in exactly the same manner as the Morphologi G3. This ensures there is no compromise on the reliability of the particle size and shape data, which is not the case with many chemical mapping and imaging techniques.
  • Chemical identification
    The instrument automatically finds particles of interest for chemical identification based on pre-defined classification rules. A Raman spectrum is acquired from the center of mass of each particle. Chemical identification is then achieved based upon established spectroscopic algorithms incorporated within the Morphologi G3-ID software. This allows enumeration of defined classes of particles as well as the reporting of component specific particle size and shape distributions.



Static automated imaging combined with Raman spectroscopy.
Morphological analysis:
Static automated imaging.
Particle size:
1 µm – 1000 µm*.
Particle properties measured:
Size, shape, transparency, count, location, chemical identification.
Particle size parameters:
Circle equivalent (CE) diameter, length, width, perimeter, area, maximum distance, sphere equivalent (SE) volume, fiber total length, and fiber width.
Particle shape parameters:
Aspect ratio, circularity, convexity, elongation, high sensitivity (HS) circularity, solidity fiber elongation, fiber straightness
Particle transparency parameters:
Intensity mean, intensity standard deviation.

Sample dispersion (Morphologi G3SE-ID only)

Integrated Sample Dispersion Unit option (Morphologi G3SE only):
Dispersion mechanism:
Sample entrainment, leading to particle shear and particle impaction.
Dispersion pressure range:
0.5 – 5 bar.
Dispersion pressure precision:
0.1 bar increments.
Injection time range:
5 - 100 msec
Sample Settling time:
1-600 sec.


Light source:
White light, brightfield diascopic and episcopic.
5M pixel 2592 x 1944 color CCD array.
Pixel width:
2.78 µm x 2.78 µm.
Optical system:
Nikon CFI 60 brightfield/darkfield system.
2.5x, 5x, 10x, 20x, 50x
Particle size:
100-1000µm, 25-420µm, 20-210µm, 20-100µm, 1-40µm,


Chemical analysis:
Raman spectroscopy.
Raman spectrometer:
Kaiser optical systems Inc. RamanRxn1.
Spectral performance:
150 cm-1 to 1850 cm-1, 6 cm-1 resolution
<500 mW (Spectrometer).
> 10 mW nominal (at sample).
Laser spot size:
3 µm at 50x magnification.
Laser safety:
Class 3B.
Chemical identification method:
Spectral correlation.
The Morphologi G3-ID and Morphologi G3SE-ID are protected by copyright and design rights, together with patents based on EP2106536A1 and US8111395B2.

Weight and dimensions:

Dimensions (W, D, H):
Main instrument: 440mm x 760mm x 750mm
Dimensions (W, D, H):
Spectrometer: 584mm x 448mm x 203mm
Main instrument: 80 kg approx.
Spectrometer: 27.7 kg

Operating environment:

100-240 V ac 50/60 Hz 6.0 A
Operating temperature (°C):
+15 to +30°C
Storage temperature:
-15 to +30°C
0–95%, non-condensing


Sample and substrate dependent. Instrument can also be used as a Morphologi G3. See Morphologi G3 page for details on performance capabilities.


Protect your investment and ensure optimized performance at all times with Malvern’s service plans.

When you purchase a Malvern product we understand that this is just the first stage of a working relationship that will last for the lifetime of the instrument. Depending on your needs, Malvern will provide the support for your business.

Help Desk


Software downloads

Malvern’s service options- choose the right plan for you:


Malvern Platinum Plan

For laboratories where maximizing instrument up-time is critical to its daily performance. Our highest level of response and the 'all inclusive' price plan takes care of those unexpected repair bills should the unfortunate occur.


Malvern Gold Plan

Enhance your laboratory productivity by maintaining instrument efficiency. Still receive that priority response, combined with specialist technical and software support, we'll keep your instrument performance on track to deliver.


Malvern Bronze Visit

For laboratories looking to optimize instrument performance, regular preventative maintenance is essential.

Platinum PlanGold PlanBronze Visit
Annual PM/PV Test
Telephone / Email Support
Priority Response
Emergency Breakdown visits*
Parts Included
Technical & Software Support
IQ/OQ (Pharma)***

*including labour & travel costs***available at an additional cost


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Particles unmasked: “What is it, and where did it come from?” Webinar - Live (English)

These are questions which are often asked about unknown particles in a variety of sample types, such as when developing (bio)pharmaceutical products, or as part of forensic investigations. This short web seminar will introduce you to new ways of usin...

Morphologi range
October 20 2015

Improved approaches for particulate characterization in biotherapeutics Webinar - Recorded (English)

Product quality and safety concerns have driven the enumeration of particulate species in injectable products. Guidelines, such as USP<787>, <788>, and <790>, describe methods for collecting accurate particle count and size data in...

Morphologi range
Date recorded:
July 30 2015

Exploring the effect of carbon microstructure on lithium-ion battery performance Application Note (English)

This application note describes the combined use of static optical microscopy and Raman spectroscopy in the Morphologi G3-ID to assess the various morphological classes of carbon for use in lithium-ion battery manufacture.  High levels of crystallini...

Characterization of protein aggregates in suspension and on a filter membrane by Morphologically-Directed Raman Spectroscopy Application Note (English)

The combination of static microscopy and Raman spectroscopy in the Morphologi G3-ID enables automated chemical identification of protein aggregates and other contaminants in a biotherapeutic sample, either in suspension via a thin-path wet cell or on...

Discriminating between polymorphs of acetaminophen using Morphologically-Directed Raman Spectroscopy (MDRS) Application Note (English)

Polymorphic conversions are an ongoing problem in the pharmaceutical industry.  Here we describe the use of Morphologically-Directed Raman Spectroscopy to distinguish and quantify particles of different polymorphic types of acetaminophen (paracetamol...

Previous page Showing results 1 - 5 of 36 Next page


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Upcoming webinar

Particles unmasked: “What is it, and where did it come from?”
(October 20 2015)

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