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The Morphologi G3-ID provides a unique capability, combining automated static imaging features of the Morphologi G3 with chemical identification of individual particles using Raman spectroscopy to enable the measurement of component specific particle size and particle shape distributions.
This fully automated instrument is designed to allow both particle characterization scientists with limited spectroscopy experience and more experienced spectroscopists to get an in-depth understanding of their particulate samples. Key features:
The Morphologi G3-ID is ideally suited to solving complex particle characterization problems where component-specific particle size and shape distributions are required. This includes measurement of components within powder blends and suspensions, along with the identification of contaminant or suspicious particles within product formulations.
The measurement workflow can be divided into three distinct steps, each of which can be automated:
When you purchase a Malvern product we understand that this is just the first stage of a working relationship that will last for the lifetime of the instrument. Some customers just need to ask an occasional question or to download a software upgrade, whilst others require a comprehensive support contract with priority call out and fixed cost of ownership. Whatever your situation Malvern will provide the right support for you.
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Particle agglomeration can compromise the clinical efficacy of pharmaceutical products and must therefore be closely controlled. This article provides practical guidance on using automated imaging for efficient agglomerate detection.
This application note details how Morphologically Directed Raman Spectroscopy (MDRS) using the Morphologi G3-ID can be applied to the forensic identification of commercially sourced white powders commonly used in hoax bio-terrorism powder attacks. It...
Oral Solid Dosage (OSD) forms still represent a significant share of the pharmaceutical market. As a result, they remain an important target for generic product developers. In this white paper we introduce a workflow for OSD product deformulation and...
Bacteria fibers are typically monitored with manual microscopy to better understand the effect of environmental factors on their growth. Here, bacteria fibers taken at different times are automatically characterised on the Morphologi G3. Fiber parame...
Deformulation of oral solid dose (OSD) products requires generic companies to determine the physical and chemical properties of the excipients and active pharmaceutical ingredients (APIs) present within the reference listed drug product (...
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