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The Malvern NanoSight range of instruments utilizes Nanoparticle Tracking Analysis (NTA) to characterize nanoparticles from 10nm -2000nm* in solution. Each particle is individually but simultaneously analyzed by direct observation and measurement of diffusion events. This particle-by-particle methodology produces high resolution results for particle size distribution and concentration, while visual validation provides users with additional confidence in their data. Both particle size and concentration are measured, while a fluorescence mode provides differentiation of labelled or naturally fluorescing particles.
* sample dependent
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Significant advances have been made in analytical technology for the characterization and identification of particles present in pharmaceutical products. With these advances comes a tremendous amount of new data with which to characterize biologics, ...
• Nanoparticle Tracking Analysis (NTA) Characterization of Gold-Labeled Adeno Associated Virus (AAV) and Other Small Viruses • NTA is an analytical tool that measures the size and concentration of virus particles. • NTA can measure virus titer in abo...
• Nanoparticle Tracking Analysis (NTA) was used to study the diffusion of silica nanoparticles functionalized with different polymers in aqueous solutions of water-soluble polymers and in dispersions of porcine gastric mucin
• It was found that th...
The area of fine and ultrafine bubble technology has seen great advancements over the last few years. Ultrafine bubble water has become used in a great deal of cleaning processes (salt, oil, dirt) and also finds uses in hydroponics, ozonation of wate...
Aggregation of both biological and synthetic materials is a serious cause for concern, posing problems at various stages of the discovery and formulation processes. Liposomes have been used in drug discovery and drug delivery for some time, and the b...
(Webinar - Recorded)
Applying complementary particle techniques for assessing comparability and biosimilarity of therapeutic products
(September 20 2016)
The Malvern NanoSight NTA system allows us to directly and reliably quantify extracellular vesicle yields from the cell lines under investigation, which is critical to this project.
Ohio State University
With NTA we are able to sensitively monitor the behavior of a nanoparticle over time in a variety of different media.
Département Environnement et Agro-biotechnologies at the CRP - Gabriel Lippmann.
NTA is a relatively new addition to the lab but is already bringing value to several areas of research.
Dr Krystelle Mafina
Queen Mary University
Malvern Instruments’ webinars, live chats and technical support are very useful and continue to help our researchers push the boundaries of materials and biomaterials science.
One of the great things about the Nanoparticle Tracking Analysis system is the unique visualization capability which enables real time empirical insight into key particle behavior, such as the propensity and rate of aggregation, as opposed to alternative techniques with often lengthy procedures.
University of Wisconsin-Milwaukee
Nanoparticle Tracking Analysis has provided us with an instantaneous way of looking at the behavior of the nanoparticles within a biological medium, providing insight unachievable with alternative analysis techniques.
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