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The Malvern NanoSight LM10 instrument provides an easy-to-use, reproducible platform for nanoparticle characterization.
The LM10 allows rapid and accurate analysis of the size distribution and concentration of all types of nanoparticles from 10nm to 2000nm in diameter, depending on the instrument configuration and sample type.
The Malvern NanoSight LM10 is a highly flexible and robust instrument that can be upgraded at any time to fit the changing needs of both routine testing and research laboratories.
The Malvern NanoSight LM10 uses the technology of Nanoparticle Tracking Analysis (NTA). This unique technology utilizes the properties of both light scattering and Brownian motion in order to obtain the size distribution and concentration measurement of particles in liquid suspension. A laser beam is passed through the sample chamber, and the particles in suspension in the path of this beam scatter light in such a manner that they can easily be visualized via a 20x magnification microscope onto which is mounted a camera. The camera operates at 30 frames per second (fps), capturing a video file of the particles moving under Brownian motion. The software tracks many particles individually and using the Stokes-Einstein equation calculates their hydrodynamic diameters.
When you purchase a Malvern product we understand that this is just the first stage of a working relationship that will last for the lifetime of the instrument. Some customers just need to ask an occasional question or to download a software upgrade, whilst others require a comprehensive support contract with priority call out and fixed cost of ownership. Whatever your situation Malvern will provide the right support for you.
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The need to characterize different properties of nanomaterials continues to grow rapidly. Since the commercialization of the technique in 2004, Nanoparticle tracking Analysis (NTA) has become increasingly prevalent in a wide variety of different rese...
Fluorescence is becoming an increasingly considered as a tool within nanoparticle characterisation. The ability to positively identify particular subsets of nanoparticles within a sample is especially important for applications in life science, drug ...
During this webinar, we will introduce the Nanoparticle Tracking Analysis (NTA) technique and discuss how it can provide a range of useful characterization information for protein corona and self-assembled albumin-drug nanoparticles. Reviews of the ...
The movement of particles in a colloidal suspension is the property we use in order to characterize the size distribution (via the Stokes-Einstein equation). We'll look at diffusion including the random Brownian motion that we require for valid appli...
In this webinar we discuss techniques for producing high quality size distribution and concentration measurements for extracellular vesicle preparations with NanoSight. For characterizing the size and concentration of EVs the focus will be on underst...
(Webinar - Recorded)
Optimizing Exosome and Extracellular Vesicle Measurements by NTA
(August 5 2015)
The Malvern NanoSight NTA system allows us to directly and reliably quantify extracellular vesicle yields from the cell lines under investigation, which is critical to this project.
Ohio State University,
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