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The Malvern NanoSight LM10 instrument provides an easy-to-use, reproducible platform for nanoparticle characterization.
The LM10 allows rapid and accurate analysis of the size distribution and concentration of all types of nanoparticles from 10nm to 2000nm in diameter, depending on the instrument configuration and sample type.
The Malvern NanoSight LM10 is a highly flexible and robust instrument that can be upgraded at any time to fit the changing needs of both routine testing and research laboratories.
The Malvern NanoSight LM10 uses the technology of Nanoparticle Tracking Analysis (NTA). This unique technology utilizes the properties of both light scattering and Brownian motion in order to obtain the size distribution and concentration measurement of particles in liquid suspension. A laser beam is passed through the sample chamber, and the particles in suspension in the path of this beam scatter light in such a manner that they can easily be visualized via a 20x magnification microscope onto which is mounted a camera. The camera operates at 30 frames per second (fps), capturing a video file of the particles moving under Brownian motion. The software tracks many particles individually and using the Stokes-Einstein equation calculates their hydrodynamic diameters.
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The need to characterize different properties of nanomaterials continues to grow rapidly. Since the commercialization of the technique in 2004, Nanoparticle tracking Analysis (NTA) has become increasingly prevalent in a wide variety of different rese...
Nanoparticle Tracking Analysis (NTA) has been widely adopted in a range of different research streams for the visualisation, sizing and counting of nanoscale materials in liquid suspension. Here the methodology behind the instrumentation will be disc...
To ensure that your NanoSight instrument is performing within specification, it is best practice to regularly measure size-traceable standards. The size standard/s used should be similar to the size of the nanoparticles which are typically measured w...
The movement of particles in a colloidal suspension is the property we use in order to characterize the size distribution (via the Stokes-Einstein equation). We'll look at diffusion including the random Brownian motion that we require for valid appli...
Fluorescence is becoming an increasingly considered as a tool within nanoparticle characterisation. The ability to positively identify particular subsets of nanoparticles within a sample is especially important for applications in life science, drug ...
(Webinar - Recorded)
NTA Virtual Demonstration
(September 22 2015)
The Malvern NanoSight NTA system allows us to directly and reliably quantify extracellular vesicle yields from the cell lines under investigation, which is critical to this project.
Ohio State University
With NTA we are able to sensitively monitor the behavior of a nanoparticle over time in a variety of different media.
Département Environnement et Agro-biotechnologies at the CRP - Gabriel Lippmann.
NTA is a relatively new addition to the lab but is already bringing value to several areas of research.
Dr Krystelle Mafina
Queen Mary University
Malvern Instruments’ webinars, live chats and technical support are very useful and continue to help our researchers push the boundaries of materials and biomaterials science.
One of the great things about the Nanoparticle Tracking Analysis system is the unique visualization capability which enables real time empirical insight into key particle behavior, such as the propensity and rate of aggregation, as opposed to alternative techniques with often lengthy procedures.
University of Wisconsin-Milwaukee
Nanoparticle Tracking Analysis has provided us with an instantaneous way of looking at the behavior of the nanoparticles within a biological medium, providing insight unachievable with alternative analysis techniques.
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