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With 30 years of chromatography and light scattering experience, the Viscotek GPC/SEC systems and detectors from Malvern provide solutions for all applications of proteins, synthetic and natural polymers.

Complete systems are available as out-of-the-box solutions for macromolecular characterization. Alternatively, upgrade an existing system through the addition of a modular detector.

The entire Viscotek range is backed by the Malvern’s global support and training network.

Viscotek systems Out-of-the-box solutions for the characterization of proteins, synthetic and natural polymers Image
Measurement
Molecular size, Molecular structure, Molecular weight, Protein aggregation
Accuracy
Technology
Gel Permeation Chromatography, Size Exclusion Chromatography, Dilute Solution Viscometry, Static Light Scattering
More information
Viscotek detectors A comprehensive range of advanced GPC/SEC detectors Image
Measurement
Molecular size, Molecular structure, Molecular weight, Protein aggregation
Accuracy
Technology
Gel Permeation Chromatography, Size Exclusion Chromatography, Static Light Scattering
More information
 
 

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Characterization of Whey Protein Isolate (WPI) using multi-detector size-exclusion chromatography Application Note (English)

In this application note, a sample of Whey Protein Isolate (WPI) was characterized using the Viscotek TDAmax. The 4 main components in this mixture were separated and individually characterized to determine molecular weight and size. ...


Keywords: English Application Note Molecular size Molecular weight Size Exclusion Chromatography Dairy products Food additives Protein aggregation Proteins Viscotek TDAmax Viscotek TDA 305 

Using Multi-Detection GPC/SEC to Determine Impact of Sterilization on Medical-Grade Polymers Article (English)

This article gives an introduction to multi-detection GPC/SEC and presents data that shows how the technique is being used to determine the impact of sterilization on medical grade poly(L-lactide).


Keywords: Polymer solutions English Article Molecular structure Molecular weight Gel Permeation Chromatography Size Exclusion Chromatography Specialty and novel polymers Injectables Viscotek TDAmax 

Viscotek 350 HT-GPC user manual (English) User Manual (English)

User manual for the Viscotek 350 HT-GPC used with Gel Permeation Chromatography/Size Exclusion Chromatography (GPC/SEC) systems


Keywords: English User Manual Viscotek systems Viscotek HT-GPC Viscotek detectors 

Characterization of hydrodynamic changes upon cation-binding to proteins Application Note (English)

Cations are specifically recognized by numerous proteins. Despite their small size, their specific interactions with highly charged residues allow them to induce significant conformational changes on their binding proteins. The protein conformational...


Keywords: English Application Note Molecular size Molecular weight Zeta potential Electrophoretic Light Scattering Size Exclusion Chromatography Viruses and vaccines Zetasizer Nano ZS Proteins Protein mobility Biological drug characterization and development Viscotek TDAmax Viscotek TDA 305 

PEGylated proteins: Optimizing conjugation reactions using triple detection SEC Application Note (English)

In this application note, interferon α-5 was conjugated with two different PEG molecules in different reactions. The individual protein and PEG molecules, as well as the PEGylated conjugates are characterized by SEC and their composition,...


Keywords: English Application Note Molecular size Molecular weight Static Light Scattering Size Exclusion Chromatography Protein aggregation Proteins Biological drug characterization and development Viscotek TDAmax Viscotek SEC-MALS Viscotek UV-PDA Detector (2600) 
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