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OmniSEC software is at the heart of all Viscotek systems, providing an integrated solution that helps you maximize the information and efficiency of your experiments. Simply load your samples and the software controls all the sequencing, enabling truly automatic unattended operation.


OmniSEC contains many convenient and productive features, and supports the following:

  • Multi detection (Single/Dual/Triple/Tetra).
  • Absolute molecular weight.
  • Protein analysis.
  • Molecular conformation/branching.
  • Copolymer analysis.
  • Mark-Howink Plots.
  • Flow Injection Polymer Analysis (FIPA).
  • Universal calibration.
  • Conventional calibration.

Key Benefits:

  • Two clicks from raw data to results.
  • Built-in, intuitive report designer.
  • Manual or fully automatic baseline setting.
  • Automatic determination of dn/dc, UV extinction coefficient and A2.
  • Proven asymmetric band broadening corrections.
  • Fully automatic process control/LIMS mode.
  • Integrated help system to guide users.
  • Full export capability of raw data, results and intermediate calculations.
  • Enables compliance with 21 CFR part 11.

How it works

OmniSEC gives direct control of any Viscotek instrument, as well as the ability to acquire and display results in real time.

After installing the software on a suitable PC, a serial cable is used to connect the computer to any Viscotek instrument. OmniSEC then performs an automatic search to detect any connected devices (such as the TDA 305 or GPCmax) and select appropriate COM ports.

After completion of this process, the user is able to control the instruments, change detector settings and set up new or existing analysis methods. At the end of the run, data can be analyzed and reports automatically generated.



Complete GPC/SEC system including Conventional, Universal, Light Scattering, Triple, Copolymer, Protein specific, and FIPA calculation modules

Output of Mn, Mw, Mz, Mp, Mw/Mn, IV [η], Rh, Rg, Branching Number, Branching Frequency , Weight Fraction, Concentration, MH-a, MH-k, dn/dc, dA/dc. A2

Data acquisition rate:
6 channels, 5Hz, unlimited acquisition time
Calculation modules:
M<sub>n</sub>, M<sub>w</sub>, M<sub>z</sub>, M<sub>p</sub>, M<sub>w</sub>/M<sub>n</sub>, IV [η], R<sub>h</sub>, R<sub>g</sub>, Branching Number, Branching Frequency, Number of Arms, Weight Fraction, Concentration, MH-a, MH-k, dn/dc, dA/dc. A<sub>2</sub>
Results output:

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Powerful protein SEC made simple! Webinar - Live (English)

This webinar will discuss how Malvern’s protein SEC measurement capabilities within the Viscotek range have developed and improved in the last year. We will also introduce the new features that are included in the latest release of OmniSEC, i...

Viscotek range,Viscotek RImax,Viscotek DSV,Viscotek 270max,Viscotek TDAmax,Viscotek SEC-MALS
September 30 2014

Keywords: English Viscotek range Molecular structure Molecular size Molecular weight Gel Permeation Chromatography Static Light Scattering Size Exclusion Chromatography Webinar - Live Eastern Time Protein aggregation Proteins Biopharmaceutical development Viscotek 270max Viscotek DSV Viscotek RImax Viscotek TDAmax Viscotek SEC-MALS 

Characterization of Whey Protein Isolate (WPI) using multi-detector size-exclusion chromatography Application Note (English)

In this application note, a sample of Whey Protein Isolate (WPI) was characterized using the Viscotek TDAmax. The 4 main components in this mixture were separated and individually characterized to determine molecular weight and size. ...

Keywords: English Application Note Molecular size Molecular weight Size Exclusion Chromatography Dairy products Food additives Protein aggregation Proteins Viscotek TDAmax Viscotek TDA 305 

Characterization of Protein-Protein Interactions using triple detection size exclusion chromatography (SEC-TD) Application Note (English)

In this application note, triple detection size exclusion chromatography (SEC-TD) is used to understand the ability of proteins to form ordered, structured complexes. The controlling mechanism behind these protein complexes is fundamental to ...

Keywords: English Application Note Molecular size Molecular weight Static Light Scattering Size Exclusion Chromatography Viruses and vaccines Proteins Biological drug characterization and development Viscotek TDAmax Viscotek TDA 305 

Using Multi-Detection GPC/SEC to Determine Impact of Sterilization on Medical-Grade Polymers Article (English)

This article gives an introduction to multi-detection GPC/SEC and presents data that shows how the technique is being used to determine the impact of sterilization on medical grade poly(L-lactide).

Keywords: Polymer solutions English Article Molecular structure Molecular weight Gel Permeation Chromatography Size Exclusion Chromatography Specialty and novel polymers Injectables Viscotek TDAmax 

Viscotek 350 HT-GPC user manual (English) User Manual (English)

User manual for the Viscotek 350 HT-GPC used with Gel Permeation Chromatography/Size Exclusion Chromatography (GPC/SEC) systems

Keywords: English User Manual Viscotek systems Viscotek HT-GPC Viscotek detectors 
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