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Dynamic light scattering (DLS), sometimes referred to as Quasi-Elastic Light Scattering (QELS), is a non-invasive, well-established technique for measuring the size and size distribution of molecules and particles typically in the submicron region, and with the latest technology lower than 1nm.
Typical applications of dynamic light scattering are the characterization of particles, emulsions or molecules, which have been dispersed or dissolved in a liquid. The Brownian motion of particles or molecules in suspension causes laser light to be scattered at different intensities. Analysis of these intensity fluctuations yields the velocity of the Brownian motion and hence the particle size using the Stokes-Einstein relationship.
Dynamic light scattering technology from Malvern Instruments offers the following advantages:
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There are many technologies available for the increased understanding of protein unfolding and stability, including calorimetry, spectroscopy, and light scattering techniques. In recent years, Raman spectroscopy has proven to be useful for the charac...
This online demo is designed to provide you with a virtual hands-on introduction to the Zetasizer Nano. You will be able to take a look at the Zetasizer Nano and some of its accessories via webcam. We will screen-share the software with you so that y...
Suspensions or dispersions of particles or droplets in a liquid medium are encountered in a variety of industries and find use in a diverse range of applications. These include liquid abrasives, ceramics, medicines, foodstuffs and inks to name a few....
The z-average diameter is the mean intensity diameter i.e. it is a diameter based upon the intensity of scattered light of a material in its native state (including electrical double layers and surface structure). The z-average is derived from a Cumulants analysis of the measured correlation curve, wherein a single particle size is assumed and a single exponential fit is applied to the autocorrelation function. It is unique to dynamic light scattering and it is sensitive to the presence of aggregates/dust due to the intensity of light scattered by any larger particles present.
As the Nanoparticle Tracking Analysis (NTA) technique has gained in popularity in recent years, comparison to Dynamic Light Scattering (DLS) results has become more frequent. When comparing results, it is important to understand the differences betwe...
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