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Dynamic light scattering (DLS), sometimes referred to as Quasi-Elastic Light Scattering (QELS), is a non-invasive, well-established technique for measuring the size and size distribution of molecules and particles typically in the submicron region, and with the latest technology lower than 1nm.

Typical applications of dynamic light scattering are the characterization of particles, emulsions or molecules, which have been dispersed or dissolved in a liquid. The Brownian motion of particles or molecules in suspension causes laser light to be scattered at different intensities. Analysis of these intensity fluctuations yields the velocity of the Brownian motion and hence the particle size using the Stokes-Einstein relationship.

Dynamic light scattering technology from Malvern Instruments offers the following advantages:

  • Accurate, reliable and repeatable particle size analysis in one or two minutes.
  • Measurement in the native environment of the material.
  • Mean size only requires knowledge of the viscosity of the liquid.
  • Simple or no sample preparation, high concentration, turbid samples can be measured directly.
  • Simple set up and fully automated measurement.
  • Size measurement of sizes < 1nm.
  • Size measurement of molecules with MW < 1000Da.
  • Low volume requirement (as little as 2µL).
  • Compliance with regulatory standards ISO 13321, ISO 22412, 21 CFR Part 11.

Related products

Zetasizer range The world's most widely used system for nanoparticle, colloid and protein size, zeta potential and molecular weight measurements. Zetasizer range - particle size, dynamic light scattering, zeta potential, protein aggregation
Molecular size, Particle size, Molecular weight, Zeta potential
Temperature range
Particle size range
0.3nm to 10µm
Dispersion type
Dynamic Light Scattering, Static Light Scattering, Size Exclusion Chromatography, Electrophoretic Light Scattering
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Explaining the difference between Non-Invasive BackScatter (NIBS) and Backscatter – they are NOT the same. Technical Note (English)

The ability to measure accurate particle size across a range of concentrations and sizes whilst maintaining consistent results is critically important in ensuring you can trust your data and develop an understanding of your application. This paper he...

Nanoparticle Tracking Analysis (NTA) Application: Better Understanding Synthetic Nanoparticle Systems Webinar - Recorded (English)

This webinar introduces the Nanoparticle Tracking Analysis (NTA) technique and how it affords useful information in various synthetic nanoparticle systems. We will discuss how NTA was used to measure the effects of certain buffers on the aggregation...

NanoSight range
Date recorded:
November 17 2015

Adhesion and cohesion Webinar - Recorded (English)

The basis of agglomeration and aggregation is the attraction that particles and particle groups have for one another. We'll outline the various forms of atttaction (van de Waals, capillary etc ) and thus show how a gecko can walk on the ceiling.

Mastersizer range
Date recorded:
November 3 2015

Silver colloids and invisible ink Webinar - Recorded (English)

In the early history of cryptography and ciphers then invisible inks using silver salts and other chemicals were used. Silver colloids were regularly used and abused in this area. Silver colloids are now finding application (and legislation) as bater...

Date recorded:
September 2 2015

Colloidal Stability & Conformational Changes in β-Lactoglobulin: Unfolding Unfolding to Self-Assembly Article (English)

A detailed understanding of the mechanism of unfolding, aggregation, and associated rheological changes is developed in this study for β-Lactoglobulin at different pH values through concomitant measurements utilizing dynamic light scattering (DLS), o...

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