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Electrophoretic Light Scattering (ELS) is a technique used to measure the electrophoretic mobility of particles in dispersion, or molecules in solution. This mobility is often converted to Zeta potential to enable comparison of materials under different experimental conditions.

The fundamental physical principle is that of electrophoresis. A dispersion is introduced into a cell containing two electrodes. An electrical field is applied to the electrodes, and particles or molecules that have a net charge, or more strictly a net zeta potential will migrate towards the oppositely charged electrode with a velocity, known as the mobility, that is related to their zeta potential.

Malvern Instruments offer leading instrumentation for the measurement of electrophoretic mobility. The Zetasizer Nano provides a simple, fast and accurate way to measure zeta potential, and uses a unique disposable capillary cell to ensure that there is no cross contamination between samples. The NanoSight NS500 measures electrostatic potential particle-by-particle to produce number-weighted, not intensity-weighted, data, avoiding any bias towards larger particles.

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Zetasizer range The world's most widely used system for nanoparticle, colloid and protein size, zeta potential and molecular weight measurements. Zetasizer range - particle size, dynamic light scattering, zeta potential, protein aggregation
Molecular size, Particle size, Molecular weight, Zeta potential
Temperature range
Particle size range
0.3nm to 10µm
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Dynamic Light Scattering, Static Light Scattering, Size Exclusion Chromatography, Electrophoretic Light Scattering
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NanoSight NS500 Single particle zeta potential platform with integrated fluidics for automation. NanoSight NS500 single particle size distribution, fluorescence, zeta potential measurment
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Colloidal Stability & Conformational Changes in β-Lactoglobulin: Unfolding Unfolding to Self-Assembly Article (English)

A detailed understanding of the mechanism of unfolding, aggregation, and associated rheological changes is developed in this study for β-Lactoglobulin at different pH values through concomitant measurements utilizing dynamic light scattering (DLS), o...

Non-aqueous zeta potential measurements of carbon black powders Application Note (English)

The measurement of the zeta potential of non-aqueous suspensions is challenging as the electrophoretic mobility of the particles is very small. Here we describe how the Zetasizer Nano in combination with a universal dip cell accessory gives excellent...

Suspension properties Masterclass 4: Using rheology to assess suspension stability Webinar - Recorded (English)

This presentation discusses the importance of particle size, zeta potential and rheology for a functional suspension, and demonstrates how these properties can be manipulated to induce dispersion stability.

Kinexus range,Zetasizer Nano range,Mastersizer range
Date recorded:
April 10 2013

Keywords: Suspensions, slurries and pastes English Kinexus range Mastersizer range Particle size Rheology and viscosity Zeta potential Dynamic Light Scattering Electrophoretic Light Scattering Webinar - Recorded Greenwich Time Zetasizer Nano range 

Introducing the new ON-LINE Zetasizer WT! – zeta potential clarifies coagulant dosing Webinar - Recorded (English)

Zeta potential or particle charge is the driving force responsible for the stability and flocculation of particles in a water treatment plant. Neutralization of this charge by oppositely charged coagulants is key for formation of stable, easily filte...

Zetasizer WT
Date recorded:
June 17 2015

Keywords: English Zeta potential Electrophoretic Light Scattering Plant optimization Water treatment Webinar - Recorded Eastern Time Zetasizer WT Water 

Measuring Zeta Potential - Laser Doppler Electrophoresis Explained Technical Note (English)

This technical note describes the technique used to measure zeta potential and discusses the technology used in the market leading range of Zetasizer instruments, the Nano series.

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