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Electrophoretic Light Scattering (ELS) is a technique used to measure the electrophoretic mobility of particles in dispersion, or molecules in solution. This mobility is often converted to Zeta potential to enable comparison of materials under different experimental conditions.

The fundamental physical principle is that of electrophoresis. A dispersion is introduced into a cell containing two electrodes. An electrical field is applied to the electrodes, and particles or molecules that have a net charge, or more strictly a net zeta potential will migrate towards the oppositely charged electrode with a velocity, known as the mobility, that is related to their zeta potential.

The velocity is measured by the laser Doppler technique. There are two implementations of this. One to determine a frequency shift, which can give a full zeta potential distribution and a second known as PALS, where the phase shift is measured. PALS is a more sensitive method, but only gives an average zeta potential value.

The Zetasizer Nano uses both techniques to give the best of both worlds.

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Zetasizer range The worlds most widely used system for nanoparticle, colloid and protein size, zeta potential and molecular weight measurements. Image
Molecular size, Particle size, Molecular weight, Zeta potential
Temperature range
Particle size range
Dispersion type
Dynamic Light Scattering, Static Light Scattering, Size Exclusion Chromatography, Electrophoretic Light Scattering
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Determining protein isoelectric point: A method comparison Application Note (English)

This application note compares the isoelectric point determined using the diffusion barrier technique against that obtained from other charge-measuring techniques. The data shown here shows very good agreement.

Keywords: English Application Note Zeta potential Electrophoretic Light Scattering Proteins Zetasizer Nano ZSP Protein mobility Biological drug characterization and development 

A recipe for success: Understanding the impact of production and environmental stresses on food emulsions Article (English)

Food Science researchers from the University of Massachusetts investigate the efficacy of different production techniques, and the subsequent influence of environmental stresses such as pH, ionic strength and temperature, on emulsion stability.

Keywords: Emulsions and creams English Article Kinexus range Zetasizer range Particle size Rheology and viscosity Zeta potential Dynamic Light Scattering Electrophoretic Light Scattering Rheometry - rotational Dairy products Drinks Spreads and sauces 

DTS1070 folded capillary cell - (replacement for DTS1060/DTS1061) Technical Note (English)

The Folded Capillary cell (DTS1070) is a maintenance-free, disposable capillary cell for size and zeta potential measurements in the Zetasizer Nano series of instruments. It is a replacement for DTS1060.

Keywords: English Technical Note Particle size Zeta potential Dynamic Light Scattering Electrophoretic Light Scattering Zetasizer Nano range 

Froth Flotation in the Mining and Minerals Industry Webinar - Recorded (English)

An introduction to the principles of froth flotation and the importance of the measurement of zeta potential

Zetasizer Nano range
Date recorded:
August 15 2013

Keywords: Suspensions, slurries and pastes English Zeta potential Electrophoretic Light Scattering Mining, minerals and metals Webinar - Recorded Greenwich Time Zetasizer Nano range 
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