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Electrophoretic Light Scattering (ELS) is a technique used to measure the electrophoretic mobility of particles in dispersion, or molecules in solution. This mobility is often converted to Zeta potential to enable comparison of materials under different experimental conditions.

The fundamental physical principle is that of electrophoresis. A dispersion is introduced into a cell containing two electrodes. An electrical field is applied to the electrodes, and particles or molecules that have a net charge, or more strictly a net zeta potential will migrate towards the oppositely charged electrode with a velocity, known as the mobility, that is related to their zeta potential.

Malvern Instruments offer leading instrumentation for the measurement of electrophoretic mobility. The Zetasizer Nano provides a simple, fast and accurate way to measure zeta potential, and uses a unique disposable capillary cell to ensure that there is no cross contamination between samples. The NanoSight NS500 measures electrostatic potential particle-by-particle to produce number-weighted, not intensity-weighted, data, avoiding any bias towards larger particles.

Related products

Zetasizer range The worlds most widely used system for nanoparticle, colloid and protein size, zeta potential and molecular weight measurements. Image
Measurement
Molecular size, Particle size, Molecular weight, Zeta potential
Temperature range
Particle size range
Dispersion type
Wet
Technology
Dynamic Light Scattering, Static Light Scattering, Size Exclusion Chromatography, Electrophoretic Light Scattering
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NanoSight NS500 With integrated fluidics for automation. Image
Measurement
Particle size, Particle concentration, Protein aggregation, Zeta potential
Particle size range
10nm to 2000nm
Technology
Nanoparticle Tracking Analysis, Electrophoretic Light Scattering
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Zeta potential measurements of high conductivity colloidal samples Application Note (English)

The diffusion barrier technique can be used for any colloidal sample with high conductivity. This application note discusses the application of the diffusion barrier technique to high conductivity samples through the measurement of various liposome s...


Keywords: Nanoparticles English Application Note Zeta potential Electrophoretic Light Scattering Specialty chemicals Colloids Liposomes and micelles Zetasizer Nano Z Zetasizer Nano ZS Zetasizer Nano ZS90 Zetasizer Nano ZSP 

How good is on-line zeta-potential measurement in water treatment? Article (English)

In this article we look at what zeta potential is and the potential role that on-line zeta potential monitoring can play in optimizing the water treatment process, specifically flocculation control. The applicability of zeta potential is illustrated ...


Keywords: English Article Zeta potential Electrophoretic Light Scattering Energy and environment Water treatment Zetasizer Nano range 

Water treatment - Optimize coagulant dosing using zeta potential Webinar - Recorded (English)

Measure of particle charge is one of the key parameters used by water plant operators to evaluate the required amount of coagulant. This presentation discusses the use of zeta potential measurement and it's advantages as an absolute and s...

Product:
Zetasizer Nano Z,Zetasizer Nano ZS,Zetasizer Nano ZS90,Zetasizer Nano ZSP
Date recorded:
August 14 2014
Language:
English

Keywords: English Zeta potential Electrophoretic Light Scattering Energy and environment Water treatment Webinar - Recorded Eastern Time Zetasizer Nano Z Zetasizer Nano ZS Zetasizer Nano ZS90 Zetasizer Nano ZSP 

Characterization of hydrodynamic changes upon cation-binding to proteins Application Note (English)

Cations are specifically recognized by numerous proteins. Despite their small size, their specific interactions with highly charged residues allow them to induce significant conformational changes on their binding proteins. The protein conformational...


Keywords: English Application Note Molecular size Molecular weight Zeta potential Electrophoretic Light Scattering Size Exclusion Chromatography Viruses and vaccines Zetasizer Nano ZS Proteins Protein mobility Biological drug characterization and development Viscotek TDAmax Viscotek TDA 305 

Microrheology: Running measurements on the Zetasizer ZSP/ZS Technical Note (English)

DLS microrheology measurements are particularly suited to the measurement of low viscosity and weakly-structured materials, such as polymer and biopolymer solutions.This technical note gives guidance about how to make a microrheology measurement and ...


Keywords: Polymer solutions English Method development Technical Note Electrophoretic Light Scattering Zetasizer Nano ZS Proteins Zetasizer Nano ZSP Microrheology 
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