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Electrophoretic Light Scattering (ELS) is a technique used to measure the electrophoretic mobility of particles in dispersion, or molecules in solution. This mobility is often converted to Zeta potential to enable comparison of materials under different experimental conditions.
The fundamental physical principle is that of electrophoresis. A dispersion is introduced into a cell containing two electrodes. An electrical field is applied to the electrodes, and particles or molecules that have a net charge, or more strictly a net zeta potential will migrate towards the oppositely charged electrode with a velocity, known as the mobility, that is related to their zeta potential.
Malvern Instruments offer leading instrumentation for the measurement of electrophoretic mobility. The Zetasizer Nano provides a simple, fast and accurate way to measure zeta potential, and uses a unique disposable capillary cell to ensure that there is no cross contamination between samples. The NanoSight NS500 measures electrostatic potential particle-by-particle to produce number-weighted, not intensity-weighted, data, avoiding any bias towards larger particles.
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Why particle size, zeta potential and rheology are important. This poster discusses the importance of particle size, zeta potential and rheology for dispersion stability and how they can be manipulated to enhance stability
Research shows that aggregation of a protein sample that occurs during electrophoretic measurements is more likely to take place at the electrodes. A new measurement method, the Diffusion Barrier Technique, described in this poster protects the prote...
High concentration, low-viscosity, stable therapeutic protein formulations are needed to enable low-volume parental administration. This article explores how a fully automated light scattering system supports the rapid screening of small volume sampl...
In this article we look at what zeta potential is and the potential role that on-line zeta potential monitoring can play in optimizing the water treatment process, specifically flocculation control. The applicability of zeta potential is illustrated ...
Measure of particle charge is one of the key parameters used by water plant operators to evaluate the required amount of coagulant. This presentation discusses the use of zeta potential measurement and it's advantages as an absolute and s...
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