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Gel Permeation Chromatography (GPC) is an analytical technique that separates dissolved macromolecules by size based on their elution from columns filled with a porous gel.
When GPC is coupled with light scattering, viscometer and concentration detectors (known as triple detection), it can measure absolute molecular weight, molecular size and intrinsic viscosity, and generate information on macromolecular structure, conformation, aggregation and branching.
By using GPC to measure molecular weight and these other properties, scientists can characterize molecules such as synthetic polymers, as well as natural polymers such as polysaccharides.
For all of these molecules, these parameters relate very closely to their performance in countless applications. With this technique:
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This technical note describes the two different ways of operating the seal wash system in the Viscotek GPCmax and VE-1122 pumps, which are essential for maximising the lifetime of seals and pistons.
A description of how advanced GPC/SEC detection can overcome inaccuracy in the measurement of molecular weight caused by deviation in the structure of the sample protein from that of the protein standards or interaction with the chromatography column...
Con una variedad de columnas para elegir, seleccionar las apropiadas asícomo los estándares para su aplicación GPC / SEC puede ser un reto. En este webinar, primero proporcionaremos una visión general de los tipos de columnas mas comunes ...
This webinar presents examples of GPC/SEC analysis of various elastomer chemistries and highlights the physical characterization information provided by this technique.
The aim of this technical note is to show through a series of application examples, how the performance specifications of the Viscotek SEC-MALS 20 are derived.
(Webinar - Recorded)
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