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Gel Permeation Chromatography GPC, also known as Size Exclusion Chromatography SEC or Gel Filtration Chromatography GFC, is a chromatographic technique that separates dissolved molecules on the basis of their size by pumping them through specialized columns containing a microporous packing material.
As the sample is separated and eluted from the column, it can be characterized by a single concentration detector (Conventional Calibration) or series of detectors (Universal Calibration and Triple Detection). Gel Permeation Chromatography GPC is used to characterize natural and synthetic polymers, biopolymers, proteins or nanoparticles.
When the Gel Permeation Chromatography GPC separation is coupled with light scattering, viscometer and concentration detectors together (triple detection), it will provide a distribution of absolute molecular weight, molecular size, and intrinsic viscosity as well as information on macromolecular structure, conformation aggregation and branching.
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This intermediate 2 day course is designed to deliver comprehensive knowledge of Malvern's line of Viscotek GPC/SEC technologies. Designed for Malvern customers who are currently using the system that have a desire to gain full understand...
Con una variedad de columnas para elegir, seleccionar las apropiadas asícomo los estándares para su aplicación GPC / SEC puede ser un reto. En este webinar, primero proporcionaremos una visión general de los tipos de columnas mas comunes ...
This webinar presents examples of GPC/SEC analysis of various elastomer chemistries and highlights the physical characterization information provided by this technique.
Comparison of SEC-LS and DLS capabilities in the detection and quantification of large protein aggregates
Tools for evaluating the stability of human recombinant albumins used in human therapeutics
Protein Applications for Advanced Multi-Detector Size-Exclusion Chromatography
Studying the effect of gamma sterilisation on intra-ocular lens materials.
Advanced Size Exclusion Chromatography Beneficial To Pharmaceutical Development
(Webinar - Recorded)
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