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Gel Permeation Chromatography (GPC) is an analytical technique that separates dissolved macromolecules by size based on their elution from columns filled with a porous gel.
When GPC is coupled with light scattering, viscometer and concentration detectors (known as triple detection), it can measure absolute molecular weight, molecular size and intrinsic viscosity, and generate information on macromolecular structure, conformation, aggregation and branching.
By using GPC to measure molecular weight and these other properties, scientists can characterize molecules such as synthetic polymers, as well as natural polymers such as polysaccharides.
For all of these molecules, these parameters relate very closely to their performance in countless applications. With this technique:
From novel polymers to polymer formulations and additives, in applications from paints and coatings to foods and pharmaceuticals, Malvern offers a range of GPC systems or individual GPC detectors including SEC-MALS to suit your application needs.
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Gel Permeation Chromatography (GPC), also known as Size Exclusion Chromatography (SEC), is a very popular analytical toll for characterizing natural and synthetic polymers. The introduction of the first differential Viscometer (Viscotek Model H100) b...
This technical note details information about maintaining Viscotek GPC/SEC systems to maximize reliability, prevent damage, reduce downtime, recognise imminent issues and minimise service visits
There is a strong global trend in automotive design that features a continuous increase in the use of conventional, performance, and novel polymeric materials. This is a result of weight savings, design flexibility, and ease of fabrication offered by...
Triple detection GPC/SEC combines measurements from multiple detectors to offer not only increased amounts of data, but also information, which is available thanks to the combination of different detectors and would not be obtainable using the indivi...
Gel Permeation Chromatography (GPC) also known as Size Exclusion Chromatography (SEC), is a very popular analytical tool for polymer characterization. Low molecular weight polymers such as polyols, epoxies and polycaprolactones (amongst others) are u...
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