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Automated imaging is a high resolution direct technique for characterizing particles. Individual particle images are captured from dispersed samples and analyzed to determine their particle size, particle shape and other physical properties. Statistically representative distributions can be constructed by measuring 10’s to 100’s of thousands of particles per measurement.

Static imaging systems require a stationary dispersed sample, whereas in dynamic imaging systems the sample flows past the image capture optics. The technique is often used in conjunction with ensemble based particle sizing methods such as laser diffraction to gain a deeper understanding of the sample or to validate the ensemble based measurements. Typical applications include:

  • Measurement of shape differences where particle size alone does not give differentiation.
  • Detection and/or enumeration of agglomerates, oversized particles or contaminant particles.
  • Size measurement of non-spherical particles such as needle shaped crystals.
  • Validation of ensemble based particle size measurements such as laser diffraction.

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Masterclass 1: Principios basicos de caracterizacion de particlulas usando un sistema automatizado para su analisis Webinar - Live (Spanish)

En este webinar, el primero de una serie, se presentaran los conceptos básicos de análisis de imágenes. Se cubriran los parámetros de medicion y cómo dicha información puede ser relacionada a problemas reales. La forma de una partícula puede afectar ...

Product:
Morphologi G3
Date:
October 29 2014
Language:
Spanish

Keywords: Morphologi G3 Particle shape Particle size Image analysis Webinar - Live Mexico Time Pharmaceutical development Drug discovery Pharmaceutical chemical development Pharmaceutical formulation and development Pharmaceutical manufacturing Spanish 

Characterisation of fiber-like bacteria on the Morphologi G3 with the wet cell accessory Application Note (English)

Bacteria fibers are typically monitored with manual microscopy to better understand the effect of environmental factors on their growth. Here, bacteria fibers taken at different times are automatically characterised on the Morphologi G3. Fiber parame...


Keywords: QA/QC and routine testing Contaminants and foreign particles Fibers English Application Note Morphologi G3 Particle shape Particle size Image analysis Water treatment University and government institutes Morphologi G3-ID 

Applying image analysis to support the development of particle sizing methods Application Note (English)

Getting a sample to a stable and reproducible state of dispersion is an important part of method development when carrying out particle size analysis. In this application note we show how the Mastersizer’s Hydro Sight accessory can be used to visuali...


Keywords: QA/QC and routine testing Root cause analysis (troubleshooting) Suspensions, slurries and pastes English Method development Application Note Mastersizer range Particle shape Particle size Image analysis Laser diffraction 

Automation of QC microscope measurements of a pharmaceutical ointment using the Morphologi particle characterisation system Application Note (English)

In Quality Control (QC) procedures many pharmaceutical companies rely on microscope-based analyses to identify, qualify and or quantify solid particles meeting specified size criteria. A specification for QC analysis is agreed with the compet...


Keywords: QA/QC and routine testing Emulsions and creams English Application Note Morphologi G3 Particle shape Particle size Image analysis Pharmaceutical formulation and development Pharmaceutical manufacturing 

Beyond Particle Size Article (English)

The use of ‘green’ cement additives like fly ash or limestone adds complexities to modern cement production. Defining the performance of these cements requires information about the component-specific particle size of the different compon...


Keywords: English Article Chemical identification Particle shape Particle size Image analysis Raman spectroscopy Cement Morphologi range 
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