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Nanoparticle Tracking Analysis (NTA) utilizes the properties of both light scattering and Brownian motion in order to obtain the particle size distribution of samples in liquid suspension.


A laser beam is passed through the sample chamber and the particles in suspension in the path of the beam scatter light in such a manner that they can be easily visualized via a long working distance, x20 magnification microscope onto which is mounted a video camera. The camera captures a video file of the particles moving under Brownian motion. The Nanoparticle Tracking Analysis (NTA) software tracks many particles individually and using the Stokes Einstein equation calculates their hydrodynamic diameters. The NanoSight range of instruments provides high resolution particle size, concentration and aggregation measurements while a fluorescence mode provides specific results for labelled particles. The range provides real time monitoring of the subtle changes in the characteristics of particle populations with all of these analyses confirmed by visual validation.

NTA_laser_block

The technique enables the simultaneous measurement of multiple characteristics saving on time and sample volumes while minimal sample preparation and instrument consumables reduces running costs on a day to day basis.

ASTM E2834-12(2012) Standard Guide for Measurement of Particle Size Distribution of Nanomaterials in Suspension by Nanoparticle Tracking Analysis (NTA). Applications include:

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NanoSight range Visualize and measure nanoparticle size and concentration Image
Measurement
Particle size, Particle concentration, Protein aggregation
Particle size range
10nm to 2000nm
Technology
Nanoparticle Tracking Analysis
More information
 
 

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NTA: Exosomes and Microvesicles - General Whitepaper (English)

The need to characterize different properties of nanomaterials continues to grow rapidly. Since the commercialization of the technique in 2004, Nanoparticle tracking Analysis (NTA) has become increasingly prevalent in a wide variety of different rese...


Keywords: English Whitepaper Particle concentration Particle size NanoSight NS500 NanoSight NS300 NanoSight LM10 Exosomes and microvesicles Nanoparticle Tracking Analysis Fluorescence detection 

NanoSight NTA 3.1 Software Release Webinar - Recorded (English)

NTA 3.1 is an exciting new development building on the NTA 3.0 platform that Malvern is offering to all users for free. It significantly improves ease-of-use, flexibility and performance through automation, new features, refinements and optimisations...

Product:
NanoSight LM10,NanoSight NS300,NanoSight NS500
Date recorded:
March 26 2015
Language:
English

Keywords: English Webinar - Recorded Eastern Time NanoSight NS500 NanoSight NS300 NanoSight LM10 Nanoparticle Tracking Analysis 

Particle Size Masterclass 2: which technique is best for me? Webinar - Recorded (English)

In the second webinar in the particle size masterclass series, we follow on from why you need to measure particle size, covered in the first masterclass, by looking at how to measure particle size. We started with considerations for choosing a partic...

Date recorded:
March 19 2015
Language:
English

Keywords: English Particle size Dynamic Light Scattering Image analysis Laser diffraction Webinar - Recorded Eastern Time Nanoparticle Tracking Analysis 

A fantastic voyage through the arena of nanoparticle drug delivery Webinar - Recorded (English)

The use of nanoparticles as drug delivery vehicles has seen a large amount of research and investment over the last decade as they have the potential for great benefits in the targeting and efficacy of drug treatments. The interest in them is largely...

Product:
Zetasizer range,Archimedes,NanoSight range
Date recorded:
March 18 2015
Language:
English

Keywords: English Zetasizer range Dynamic Light Scattering Webinar - Recorded Eastern Time Resonant mass measurement Archimedes NanoSight range Nanoparticle Tracking Analysis 

A virtual demonstration of Nanoparticle Tracking Analysis Webinar - Live (English)

This virtual demonstration will give you a brief overview of Nanoparticle Tracking Analysis (NTA). Using NS300 hardware and NTA3.0 software, the analysis of a sample will be covered from sample introduction through to data export and interpretation i...

Product:
NanoSight range
Date:
January 13 2015
Language:
English

Keywords: English Particle concentration Particle size Webinar - Live Eastern Time Protein aggregation NanoSight range Nanoparticle Tracking Analysis 
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