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Raman spectroscopy is an established spectroscopic technique for measuring the chemical identity and structure of materials across many industries, including pharmaceuticals, fine chemicals, minerals and foods.
Raman spectroscopy has a very high chemical specificity and is routinely used to differentiate between different polymorphs of the same compound for example. When used in conjunction with static image analysis it provides a powerful means of measuring the chemical identity of individually dispersed particles within a sample.
Applications of this technique include:
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Malvern Instruments welcomes Prof. Dr. John F. Carpenter, from the University of Colorado Center for Pharmaceutical Biotechnology, as a guest presenter contributing to the company’s current series of webinars. Professor Carpenter is a ren...
The non-invasive and non-destructive determination of numerous physicochemical properties of protein therapeutics and their aggregates is critical for developing formulation conditions that enhance product efficacy, stability and manufacturability. M...
Using the Morphologi G3-ID, the particle size and shape distributions for individual cement componets can be measured within cement blends, aiding understanding of how different cement types perform during development and production.
The Morphologi G3-ID provides, by automatically quantifying, the percent of each chemical, both active and diluent, a robust “fingerprint” of the illicit drug sample, that can potentially be used to link a street drug seizure back to the ...
The Morphol;ogi G3-ID can be used to generate component-specific particle size and shape data required to aid the reverse engineering of solid oral dose formulations. Here, we provide an example case study for a powder formulation.
Chemical Acquisition and Raman Spectral Processing methods used with the Morphologi G3-ID
Introduction to the Morphologi G3-ID
Identify, quantify & characterize adulterants and diluents in illicit drugs using Morphologi G3-ID
Component Characterization of Cements using Morphologi G3-ID
Reverse engineering of a pharmaceutical formulation using the Morphologi G3-ID
(Webinar - Recorded)
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