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Raman spectroscopy is an established spectroscopic technique for measuring the chemical identity and structure of materials across many industries, including pharmaceuticals, fine chemicals, minerals and foods.

Raman spectroscopy has a very high chemical specificity and is routinely used to differentiate between different polymorphs of the same compound for example. When used in conjunction with static image analysis it provides a powerful means of measuring the chemical identity of individually dispersed particles within a sample.

Applications of this technique include:

  • Chemically specific particle characterization of ingredients in mixtures
  • Identification of contaminants or outlier particles
  • Quantification of chemical composition in mixtures by particle count.

Related products

Morphologi G3-ID Automated measurement of particle size, shape and chemical identity. Image
Measurement
Particle shape, Particle size, Chemical identification
Particle size range
1µm to 1000µm
Technology
Image analysis, Raman spectroscopy
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Zetasizer Helix Characterize secondary and tertiary structure to develop mechanistic insight into oligomerization and aggregation. Image
Measurement
Protein aggregation, Zeta potential, Protein mobility, Molecular size, Molecular weight
Spectral performance
150cm-¹ to 1850cm-¹
Technology
Raman spectroscopy, Dynamic Light Scattering, Static Light Scattering, Electrophoretic Light Scattering
More information
 
 

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Applying complementary particle techniques for assessing comparability and biosimilarity of therapeutic products Webinar - Live (English)

Significant advances have been made in analytical technology for the characterization and identification of particles present in pharmaceutical products. With these advances comes a tremendous amount of new data with which to characterize biologics, ...

Product:
Archimedes,Zetasizer range,Viscotek SEC-MALS,Morphologi G3-ID,NanoSight range
Date:
September 20 2016
Language:
English


Rapid Generic Pharmaceutical Product Development Webinar - Recorded (English)

In a recent newsletter, the US FDA highlighted the important role Morphologically-Directed Raman Spectroscopy (MRDS) can play in supporting the development of generic drug products. The component-specific particle size and shape distribution data gen...

Product:
Morphologi G3-ID
Date recorded:
July 12 2016
Language:
English


Monitoring the impact of processing on the size and shape of API particles Webinar - Recorded (English)

As the pharmaceutical industry continues to move towards a quality by design (QbD) paradigm, the design and control of active pharmaceutical ingredient (API) particle characteristics, in particular the control of API particle size and habit with resp...

Product:
Morphologi G3-ID,Morphologi G3
Date recorded:
June 21 2016
Language:
English


Forensic soil analysis explained Webinar - Recorded (English)

This presentation explores the relevance of soil analysis in forensic science. It presents the use of Morphologically-Directed Raman Spectroscopy (MDRS) and its potential to be a valuable tool for forensic soil analysis due to its non-destructive, au...

Product:
Morphologi G3-ID
Date recorded:
May 10 2016
Language:
English


Combining Dynamic Light Scattering and Raman Spectroscopy for the analysis of protein structure and stability Webinar - Recorded (English)

There are many technologies available for the increased understanding of protein unfolding and stability, including calorimetry, spectroscopy, and light scattering techniques. In recent years, Raman spectroscopy has proven to be useful for the charac...

Date recorded:
March 15 2016
Language:
English

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