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Raman spectroscopy is an established spectroscopic technique for measuring the chemical identity and structure of materials across many industries, including pharmaceuticals, fine chemicals, minerals and foods.

Raman spectroscopy has a very high chemical specificity and is routinely used to differentiate between different polymorphs of the same compound for example. When used in conjunction with static image analysis it provides a powerful means of measuring the chemical identity of individually dispersed particles within a sample.

Applications of this technique include:

  • Chemically specific particle characterization of ingredients in mixtures
  • Identification of contaminants or outlier particles
  • Quantification of chemical composition in mixtures by particle count.

Related products

Morphologi G3-ID Automated measurement of particle size, shape and chemical identity. Image
Measurement
Particle shape, Particle size, Chemical identification
Particle size range
1µm to 1000µm
Technology
Image analysis, Raman spectroscopy
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Improved understanding of the thermal stability of a monoclonal antibody and its modified version by use of DLS/Raman spectroscopy Whitepaper (English)

Use of DLS combined with Raman spectroscopy simultaneously monitors both the colloidal and conformational stability of a template monoclonal antibody (mAb) and a modified monoclonal antibody (mmAb) and provides significant insights into the mechanist...


Keywords: English Whitepaper Molecular structure Molecular size Dynamic Light Scattering Electrophoretic Light Scattering Raman spectroscopy Static Light Scattering Protein aggregation Proteins Biological drug characterization and development Bioformulation development Zetasizer Helix 


Use of DLS/Raman to study the thermal unfolding process of lysozyme Whitepaper (English)

Use of DLS combined with Raman spectroscopy to monitor changes in secondary and tertiary protein structural markers together with size changes to more fully understand the unfolding behavior of lysozyme and other proteins.


Keywords: English Whitepaper Molecular structure Molecular size Dynamic Light Scattering Electrophoretic Light Scattering Raman spectroscopy Static Light Scattering Protein aggregation Proteins Biological drug characterization and development Bioformulation development Zetasizer Helix 
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