Gel Permeation Chromatography/Size Exclusion Chromatography (GPC/SEC) systems

Viscotek GPC/SEC range

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Differential Viscometer Detector (for 270max)

Viscotek TDAmax system for temperature controlled Gel Permeation Chromatography
Viscotek TDAmax system for temperature controlled Gel Permeation Chromatography

The differential viscometer detector provides a direct and sensitive measurement of intrinsic viscosity and allows for the determination of molecular size, conformation and structure.

Viscotek invented and patented the first differential viscometer detector and that experience is packed into the 270 giving high sensitivity, excellent baseline stability and wide applications flexibility. In the measuring flow-path, the use of inert capillaries means the analysis of proteins and other biomolecules can be completed with confidence.

For polymers and polysaccharides, the viscosity information shows the complete Mark-Houwink relationship of molecular weight to intrinsic viscosity at all points to determine structure and measure the branching properties such as number of branches vs. molecular weight.

For proteins, the determined intrinsic viscosity gives a clear measurement of the protein density.

When used together with the molecular weight data from the light scattering detector, the intrinsic viscosity gives a direct measurement of protein or polymer size (RH) with sensitivity down to < 1 nm radius.

Rh

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Featured presentations and application notes:

 
Requires free registration and login Application communication: Universal calibration to study star-branched polystyrene
It is shown in this application communication that the number of branches of a star polymer can be assessed by merely adding a viscometer detector to a conventional chromatography system.
  Download the Application Note: Universal calibration to study star-branched polystyrene
 
Requires free registration and login Application communication: Determination of polymer structure by GPC
It is advantageous to use light scattering to determine molecular weights provided the signals are sufficiently intensive strong. Triple detection combines these detection capabilities into a single system to give molecular weight and structure without limitations.
  Download the Application Note: Determination of polymer structure by GPC
 
Requires free registration and loginOn-demand presentation: Quality Control Analysis of CPVC Pipe Using Advanced Detection GPC
Chlorinated polyvinylchloride (CPVC) is a common thermoplastic used for applications requiring an economical material for liquid handling. The process of manufacturing CPVC pipe follows two basic steps. The material is first compounded with a variety of additives to control both functional an aesthetic properties and is then extruded under heat and pressure to mold the final product. In some cases, the final product does not contain the required physical properties. The material’s performance can be directly linked to the structural deficiencies of the CPVC. To monitor these changes, the CPVC can be isolated, separated by GPC, and analyzed using advanced detection to determine inconsistencies in the structural properties that may arise during the extrusion process. These changes, whether they are structural or chemical, can be correlated back to the stability of the virgin CPVC used, preventing further processing of defective material
  Start the on-line presenation: Quality Control Analysis of CPVC Pipe Using Advanced Detection GPC

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