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Viruses and vaccines
Conjugation influences biodistribution for targeted delivery and reducing toxicity.
Vaccines are developed either as prophylactic treatment to prevent future infection or as a therapeutic such as in the case of cancer vaccine. Vaccines are produced using different strategies; ranging from using inactivated or attenuated virus, toxic compounds, DNA plasmids, bacterial polysaccharides conjugated to proteins to protein sub-units from the virus surface to stimulate the body’s immune defense.
Malvern technologies can help you in your virus research or vaccine production in the following application areas:
- Determining size and size distribution of viruses
- Detecting protein aggregates
- Measuring protein and protein complex stability
- Monitoring adjuvant size, size distribution and stability
- Quantifying composition analysis of conjugated vaccine complexes.
Malvern solutions for Viruses and vaccines
Characterization of Rice Dwarf Virus
This application note presents the characterization of a virus protein by light scattering to find its size and molecular weight.
Interactions of Bovine Serum Albumin with Aluminum Polyoxocations
The Zetasizer Nano has been successfully used to determine the size of Al13 and Al30-mers and characterize the size of complexes formed between these aluminum polyoxocations and bovine serum albumin.
