Viruses and vaccines
Conjugation influences biodistribution for targeted delivery and reducing toxicity.
Vaccines are developed either as prophylactic treatment to prevent future infection or as a therapeutic such as in the case of cancer vaccine. Vaccines are produced using different strategies; ranging from using inactivated or attenuated virus, toxic compounds, DNA plasmids, bacterial polysaccharides conjugated to proteins to protein sub-units from the virus surface to stimulate the body’s immune defense.
Malvern technologies can help you in your virus research or vaccine production in the following application areas:
- Determining size and size distribution of viruses
- Detecting protein aggregates
- Measuring protein and protein complex stability
- Monitoring adjuvant size, size distribution and stability
- Quantifying composition analysis of conjugated vaccine complexes.