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Malvern Podcasts

Malvern now offers you the opportunity to download our audio podcasts of key presentations. Listen to Malvern specialists and guest presenters from industry and academia on virtually all subjects related to various aspects of particle characterization and rheology.

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Chemical Imaging

A short overview of the use of near infrared chemical imaging for the analysis of granules.
Language: English
Duration: 7 minutes

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An overview of how near infrared chemical imaging can be used to evaluate batch-to-batch variation in products.
Language: English
Duration: 8 minutes

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The incorporation of active pharmaceutical ingredients (API) into solid dosage forms requires careful considerations to achieve both the bioavailability and stability profiles desired. In this presentation, we discuss some examples of analyses performed using NIR chemical imaging to investigate the stability of amorphous and crystalline APIs in tablets. The presentation will described some preliminary tests that should be performed to assess the suitability of NIR imaging for the task and explore different ways to measure the API in the matrix.
Language: English
Duration: 1 hour 3 minutes

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Dynamic Light Scattering

The new Zetasizer MicroV instruments is a dynamic light scattering instrument ideally suited to protein characterization.
Language: English
Duration: 8 minutes

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Particle sizing by dynamic light scattering with particular reference to the Zetasizer Nano series of instruments and the High Performance Particle Sizer (HPPS) instrument. An overview of dynamic light scattering theory, an introduction to the software and sample preparation for measurement.
Language: English
Duration: 1 hour 18 minutes

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The ability to automate particle size and scattering intensity trend measurements can be a major advantage in many applications. Processes such as aggregation, sedimentation, solubilization and changes in molecular conformation can be followed by monitoring changes in the size and scattering intensity of the sample. The Zetasizer Nano range has the capability of automating the measurement of particle size and scattering intensity as a function of temperature or time. This presentation discusses the trend measurement options with application examples.
Language: English
Duration: 42 minutes

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This seminar reviews the existing international standards for light scattering (Laser Diffraction and Dynamic Light Scattering) including ISO13320, ISO13321, ISO22412 and ASTM 2490-09. It will show how Malvern's light scattering products (Mastersizer and Zetasizer ranges) comply with the salient and vital aspects of these standards such as calibration/verification and repeatability
Language: English
Duration: 23 minutes

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Laser Diffraction

Guide to Mastersizer Accessories
Language: English
Duration: 11 minutes

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This presentation describes how particle properties influence the rheology of suspensions and how complementary techniques can be used to understand these complex systems.
Language: English
Duration: 49 minutes

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This introductory seminar deals with the fundamental statistical descriptors of particle size. In this session we will deal with what different techniques of particle sizing actually measure.
Language: English
Duration: 1 hour 10 minutes

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Ever wondered how a laser diffraction system works? This web presentation will introduce the basic principles behind the technique, explaining how a laser diffraction measurement is carried out, how particle size distributions are calculated and how sample presentation is achieved. Issues relating to the comparison of laser diffraction results with other techniques will also be addressed.
Language: English
Duration: 47 minutes

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This presentation outlines the process by which sampling and dispersion is achieved during laser diffraction measurements, with reference to the guidance provided in ISO13320, USP <429> and EP 2.9.31.
Language: English
Duration: 54 minutes

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On-Line/In-Line Process Particle Sizing

This presentation discusses how Malvern`s Automated Liquid Particle Size Analyzer - Insitec LPS brings the reliability and accuracy of laser diffraction to wet processes.
Language: English
Duration: 32 minutes

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This presentation provides an overview of the Malvern Process product range.
Language: English
Duration: 13 minutes

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This presentation will review how taking product quality measurements into the process can assist the optimization of Portland cement production.
Language: English
Duration: 48 minutes

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Granulation is an important unit operation for the pharmaceutical sector and is widely used to improve the flow properties and consistency of tableting blends, amongst other processing benefits. The Parsum probe IPP70 utilizes the technique of Spatial Filter Velocimetry and has proved to be a valuable tool in the pharmaceutical industry. The recently released pharma client software “Parsum view” for the Parsum IPP70 enables GMP-compliant data handling and storage with features such as audit trail, user access control, and safe data storage.
Language: English
Duration: 52 minutes

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Particle Shape

Introduction to the Foreign Particulate Matter analysis application on the Morphologi G3.
Language: English
Duration: 10 minutes

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An introduction to the Morphologi G3 automated particle characterization system, which combines high quality images with statistically significant particle shape and particle size measurements.
Language: English
Duration: 9 minutes

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Rheology

This presentation takes the user through the definitions used in rheology and gives an overview of the four common test methods used with a rotational rheometer, namely: viscometry, oscillation, creep and relaxation.
Language: English
Duration: 48 minutes

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A modified filament stretching extensional rheometer developed at MIT was sent to the International Space Station (ISS) aboard the Space Shuttle Discovery in 2007. In 2008, 45 samples consisting of a dilute solution (0.025 wt. %) of a narrow polydispersity high molecular weight polystyrene dissolved in oligomeric styrene oil have been tested in microgravity, 217 miles above our heads. In this talk, Dr. Johannes Soulages will give us an update on the effects of a preshear history on the transient extensional viscosity of a dilute polymer solution in a uniaxial stretching flow.
Language: English
Duration: 44 minutes

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Viscotek GPC/SEC

Size Exclusion Chromatography (SEC), also called Gel Permeation Chromatography (GPC) is a separation technique used to analyze the molecular weight and molecular weight distribution.
Language: English
Duration: 52 minutes

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Triple detection is used with size-exclusion chromatography to characterize polymer distributions. Polysaccharides are natural polymers that can be measured using this technique. Use of triple detection allows molecular weight, size and concentration of polysaccharides to be determined and also giving information about structure. This webinar will describe the technique and provide some application examples.
Language: English
Duration: 38 minutes

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Triple detection is used with size-exclusion chromatography to separate and characterize molecules such as proteins. Using triple detection allows the molecular weight and molecular size of a protein to be calculated independently of each other and retention time. This webinar will describe the technique and provide some example application data.
Language: English
Duration: 49 minutes

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This webinar will discuss the theoretical basis and practical aspects of light scattering measurements at one angle and when right angle light scattering or low angle light scattering is appropriate as well as a comparison with other light scattering techniques.
Language: English
Duration: 32 minutes

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Zeta Potential

Cleaning and preparing a zeta potential capillary and dip cell for measurement in a Zetasizer Nano instrument
Language: English
Duration: 14 minutes

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Zeta potential is the electrical potential which exits at the hydrodynamic plane of shear of a particle. The zeta potential depends on both the particle surface and the dispersant. Particles interact according to the magnitude of zeta potential , not their surface charge and therefore zeta potential can be used to predict dispersion stability.
Language: English
Duration: 19 minutes

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