Gel Permeation Chromatography GPC
Gel Permeation Chromatography GPC for measurement of polymer molecular weight, size and structure
Gel Permeation Chromatography GPC, also known as Size Exclusion Chromatography SEC or Gel Filtration Chromatography GFC, is a chromatographic technique that separates dissolved molecules on the basis of their size by pumping them through specialized columns containing a microporous packing material.
As the sample is separated and eluted from the column, it can be characterized by a single concentration detector (Conventional Calibration) or series of detectors (Universal Calibration and Triple Detection). Gel Permeation Chromatography GPC is used to characterize natural and synthetic polymers, biopolymers, proteins or nanoparticles.
When the Gel Permeation Chromatography GPC separation is coupled with light scattering, viscometer and concentration detectors together (triple detection), it will provide a distribution of absolute molecular weight, molecular size, and intrinsic viscosity as well as information on macromolecular structure, conformation aggregation and branching.
Systems for GPC/SEC:
Malvern solutions for Gel Permeation Chromatography (GPC/SEC)
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