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Raman spectroscopy
Chemical identification of particulates
Raman spectroscopy is an established spectroscopic technique for measuring the chemical identity and structure of materials across many industries, including pharmaceuticals, fine chemicals, minerals and foods.
Raman spectroscopy has a very high chemical specificity and is routinely used to differentiate between different polymorphs of the same compound for example. When used in conjunction with static image analysis it provides a powerful means of measuring the chemical identity of individually dispersed particles within a sample.
Applications of this technique include:
- Chemically specific particle characterization of ingredients in mixtures
- Identification of contaminants or outlier particles
- Quantification of chemical composition in mixtures by particle count.
Raman spectroscopy products
Morphologi G3-ID
Automated chemical identification of particulates.
This system can measure: Chemical identification, Particle shape, Particle size
Dispersion Type: Wet, Dry
See the Morphologi G3-ID
This system can measure: Chemical identification, Particle shape, Particle size
Dispersion Type: Wet, Dry
See the Morphologi G3-ID
Malvern solutions for Raman spectroscopy
Introducing the Morphologi G3–ID The future of particle characterization
This web seminar will introduce the new Morphologi G3-ID instrument. It will cover what the instrument is, how it works, and how it can be used for applications...
Component specific particle characterisation of dry powder inhalable drug products
This application note describes how the combination of automated image analysis with Raman spectroscopy in the Morphologi G3-ID can be applied...
Generic versus Innovator: an In-Vitro Bioequivalence Study with the G3-ID
A generic drug is defined as being “identical or bioequivalent to a brand name drug”1. Generic drugs approved by the U.S. Food and Drug Administration (FDA)...
Component specific particle characterisation of active component(s) in a topical cream product
Most pharmaceutical products comprise active and inactive component(s) that are blended in some way. Although the particle size distribution of the individual...
Laser diffraction and automated imaging - complementary techniques for nasal spray development
Together the techniques of laser diffraction and automated particle imaging support the fast, cost-effective development of nasal spray products, simultaneously providing the data required for regulatory...
