Proteine und Antikörper
Proteins form the major building blocks of life. Many recent pharmaceutical advances (e.g. therapeutics, antibodies) are based on detailed knowledge and characterization of the underlying proteins involved.
How do you know if the protein is well-behaved in the buffer supplied?
What is the true form of the protein in solution?
Achieve the best possible competitive advantage by:
- Optimizing protein crystallization conditions
- Measuring at true concentrations used in research environment
- Determining absolute molecular weight and polydispersity
- Assessing the importance of the second virial coefficient
- Characterizing protein homogeneity by dynamic light scattering
- Combining chromatography with dynamic light scattering to determine size and a rapid estimation of molecular weight
In this section
Protein characterization case studies Protein structure is a key parameter in the functions of proteins. Size and zeta potential can provide valuable information when characterizing the factors that can affect structure such as pH, buffer conditions, temperature and even time.
Protein characterization overview Dynamic light scattering offers additional information about your protein sample. The non-invasive protein characterization technique is fast, accurate, simple to perform, and you can recover the sample!
Malvern equipment for protein characterization and automation
Find out more about the Zetasizer Nano: performance, sensitivity, minimum volume, temperature range, software.
The Zetasizer Nano can be used in conjunction with the MPT-2 titrator for automated, unattended screens of different solvent conditions (pH, salt).